SCG2 (secretogranin II)

2007-02-01  

Identity

HGNC
SCG2
LOCATION
2q36.1
LOCUSID
7857
ALIAS
CHGC,EM66,SN,SgII
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7857
MIM: 118930
HGNC: 10575
Ensembl: ENSG00000171951

Variants:

dbSNP: 7857
ClinVar: 7857
TCGA: ENSG00000171951
COSMIC: SCG2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171951ENST00000305409P13521
ENSG00000171951ENST00000421386C9JQI2
ENSG00000171951ENST00000433889C9JDT0

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
hypothalamus
thyroid gland
adrenal gland
pituitary gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
378486722024Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF-κB pathways.0
381845552024Circulating secretoneurin level reflects angiographic coronary collateralization in stable angina patients with chronic total occlusion.0
382615662024Prognostic value of plasma secretoneurin concentration in patients with heart failure with reduced ejection fraction in one-year follow-up.0
378486722024Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF-κB pathways.0
381845552024Circulating secretoneurin level reflects angiographic coronary collateralization in stable angina patients with chronic total occlusion.0
382615662024Prognostic value of plasma secretoneurin concentration in patients with heart failure with reduced ejection fraction in one-year follow-up.0
370230802023Investigation of secretoneurin as a potential biomarker of brain injury in very preterm infants: A pilot study.1
379336402023[High expression of secretogranin II increases oxaliplatin resistance of colorectal cancer cells].0
370230802023Investigation of secretoneurin as a potential biomarker of brain injury in very preterm infants: A pilot study.1
379336402023[High expression of secretogranin II increases oxaliplatin resistance of colorectal cancer cells].0
353412742022AGTR1, PLTP, and SCG2 associated with immune genes and immune cell infiltration in calcific aortic valve stenosis: analysis from integrated bioinformatics and machine learning.0
358445562022SCG2: A Prognostic Marker That Pinpoints Chemotherapy and Immunotherapy in Colorectal Cancer.6
353412742022AGTR1, PLTP, and SCG2 associated with immune genes and immune cell infiltration in calcific aortic valve stenosis: analysis from integrated bioinformatics and machine learning.0
358445562022SCG2: A Prognostic Marker That Pinpoints Chemotherapy and Immunotherapy in Colorectal Cancer.6
341601382021Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia-inducible factor-1α in colorectal cancer.15

Citation

Dessen P

SCG2 (secretogranin II)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43777/scg2-(secretogranin-ii)