Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2150
MIM: 600933
HGNC: 3538
Ensembl: ENSG00000164251
Variants:
dbSNP: 2150
ClinVar: 2150
TCGA: ENSG00000164251
COSMIC: F2RL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164251 | ENST00000296677 | P55085 |
| ENSG00000164251 | ENST00000514165 | D6RJH3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37972702 | 2024 | Bcl-xL mediates interferon-beta secretion by protease-activated receptor 2 deficiency through the mitochondrial permeability transition pore in colorectal cancer metastasis. | 0 |
| 38166153 | 2024 | A novel trypsin of Trichinella spiralis mediates larval invasion of gut epithelium via binding to PAR2 and activating ERK1/2 pathway. | 0 |
| 38440826 | 2024 | Protease-activated receptor 2 drives migration in a colon cancer cell line but not in noncancerous human epithelial cells. | 0 |
| 37972702 | 2024 | Bcl-xL mediates interferon-beta secretion by protease-activated receptor 2 deficiency through the mitochondrial permeability transition pore in colorectal cancer metastasis. | 0 |
| 38166153 | 2024 | A novel trypsin of Trichinella spiralis mediates larval invasion of gut epithelium via binding to PAR2 and activating ERK1/2 pathway. | 0 |
| 38440826 | 2024 | Protease-activated receptor 2 drives migration in a colon cancer cell line but not in noncancerous human epithelial cells. | 0 |
| 36351795 | 2023 | Human Induced Pluripotent Stem Cell-Derived Keratinocyte-Like Cells for Research on Protease-Activated Receptor 2 in Nonhistaminergic Cascades of Atopic Dermatitis . | 1 |
| 36629588 | 2023 | Protease-activated receptor type 2 activation downregulates osteogenesis in periodontal ligament stem cells. | 0 |
| 36709122 | 2023 | [The expression and significance of protease activated receptor 2 in ovarian epithelial carcinoma]. | 0 |
| 37060079 | 2023 | Protease secretions by the invading blastocyst induce calcium oscillations in endometrial epithelial cells via the protease-activated receptor 2. | 0 |
| 37278449 | 2023 | Comparison of pancreatic enzyme abnormalities and protease-activated receptor-2-positive eosinophils in the duodenum of patients with functional dyspepsia-irritable bowel syndrome overlap with functional dyspepsia alone in Asian populations. | 0 |
| 37395651 | 2023 | Shear Stress Drives the Cleavage Activation of Protease-Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells. | 1 |
| 37827223 | 2023 | PAR2 deficiency tunes inflammatory microenvironment to magnify STING signalling for mitigating cancer metastasis via anionic CRISPR/Cas9 nanoparticles. | 0 |
| 38139455 | 2023 | Single-Nucleotide Polymorphisms of the PAR2 and IL-17A Genes Are Significantly Associated with Chronic Pain. | 0 |
| 36351795 | 2023 | Human Induced Pluripotent Stem Cell-Derived Keratinocyte-Like Cells for Research on Protease-Activated Receptor 2 in Nonhistaminergic Cascades of Atopic Dermatitis . | 1 |
Citation
Dessen P
F2RL1 (F2R like trypsin receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43801/f2rl1-(f2r-like-trypsin-receptor-1)
