Identity
HGNC
LOCATION
9p21.1
LOCUSID
ALIAS
B4GAL-T1,CDG2D,GGTB2,GT1,GTB,beta4Gal-T1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2683
MIM: 137060
HGNC: 924
Ensembl: ENSG00000086062
Variants:
dbSNP: 2683
ClinVar: 2683
TCGA: ENSG00000086062
COSMIC: B4GALT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000086062 | ENST00000379731 | P15291 |
| ENSG00000086062 | ENST00000535206 | Q86XA6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37198983 | 2023 | Analysis of the Interaction of UBE2Q1 with B4GALT1 and P53: Experimental and Molecular Modeling Study. | 0 |
| 37303063 | 2023 | B4GALT1 promotes immune escape by regulating the expression of PD-L1 at multiple levels in lung adenocarcinoma. | 7 |
| 37328064 | 2023 | In-Depth Mass Spectrometry Analysis Reveals the Plasma Proteomic and N-Glycoproteomic Impact of an Amish-Enriched Cardioprotective Variant in B4GALT1. | 1 |
| 37198983 | 2023 | Analysis of the Interaction of UBE2Q1 with B4GALT1 and P53: Experimental and Molecular Modeling Study. | 0 |
| 37303063 | 2023 | B4GALT1 promotes immune escape by regulating the expression of PD-L1 at multiple levels in lung adenocarcinoma. | 7 |
| 37328064 | 2023 | In-Depth Mass Spectrometry Analysis Reveals the Plasma Proteomic and N-Glycoproteomic Impact of an Amish-Enriched Cardioprotective Variant in B4GALT1. | 1 |
| 33238000 | 2021 | Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs. | 8 |
| 33309857 | 2021 | Galactosyltransferase B4GALT1 confers chemoresistance in pancreatic ductal adenocarcinomas by upregulating N-linked glycosylation of CDK11(p110). | 15 |
| 34855475 | 2021 | Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen. | 10 |
| 33238000 | 2021 | Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs. | 8 |
| 33309857 | 2021 | Galactosyltransferase B4GALT1 confers chemoresistance in pancreatic ductal adenocarcinomas by upregulating N-linked glycosylation of CDK11(p110). | 15 |
| 34855475 | 2021 | Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen. | 10 |
| 31800099 | 2020 | Reduced CETP glycosylation and activity in patients with homozygous B4GALT1 mutations. | 3 |
| 32027290 | 2020 | [Effect of B4GALT1 on Proliferation of Its Co-cultured Human Acute Myeloid Leukemia Cell Line in Bone Marrow Stromal Cells]. | 0 |
| 32157688 | 2020 | B4GALT1-congenital disorders of glycosylation: Expansion of the phenotypic and molecular spectrum and review of the literature. | 4 |
Citation
Dessen P
B4GALT1 (beta-1,4-galactosyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43805/b4galt1-(beta-1-4-galactosyltransferase-1)
