Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6242
MIM: 602288
HGNC: 10466
Ensembl: ENSG00000114993
Variants:
dbSNP: 6242
ClinVar: 6242
TCGA: ENSG00000114993
COSMIC: RTKN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000114993 | ENST00000233330 | Q9BST9 |
| ENSG00000114993 | ENST00000272430 | Q9BST9 |
| ENSG00000114993 | ENST00000305557 | Q9BST9 |
| ENSG00000114993 | ENST00000640304 | A0A1W2PPZ2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 27922690 | 2017 | MicroRNA-152 inhibits tumor cell growth by directly targeting RTKN in hepatocellular carcinoma. | 16 |
| 27922690 | 2017 | MicroRNA-152 inhibits tumor cell growth by directly targeting RTKN in hepatocellular carcinoma. | 16 |
| 26935528 | 2016 | Inhibition of rhotekin exhibits antitumor effects in lung cancer cells. | 6 |
| 27498032 | 2016 | Let-7a inhibits tumor cell growth and metastasis by directly targeting RTKN in human colon cancer. | 16 |
| 26935528 | 2016 | Inhibition of rhotekin exhibits antitumor effects in lung cancer cells. | 6 |
| 27498032 | 2016 | Let-7a inhibits tumor cell growth and metastasis by directly targeting RTKN in human colon cancer. | 16 |
| 26349972 | 2015 | Effect of RTKN on progression and metastasis of colon cancer in vitro. | 6 |
| 26349972 | 2015 | Effect of RTKN on progression and metastasis of colon cancer in vitro. | 6 |
| 22964635 | 2013 | Coupling S100A4 to Rhotekin alters Rho signaling output in breast cancer cells. | 29 |
| 22964635 | 2013 | Coupling S100A4 to Rhotekin alters Rho signaling output in breast cancer cells. | 29 |
| 22228765 | 2012 | Protein kinase D regulates RhoA activity via rhotekin phosphorylation. | 0 |
| 22228765 | 2012 | Protein kinase D regulates RhoA activity via rhotekin phosphorylation. | 0 |
| 19294487 | 2009 | Interaction of a multi-domain adaptor protein, vinexin, with a Rho-effector, Rhotekin. | 17 |
| 19360360 | 2009 | miR-145 inhibits breast cancer cell growth through RTKN. | 75 |
| 19294487 | 2009 | Interaction of a multi-domain adaptor protein, vinexin, with a Rho-effector, Rhotekin. | 17 |
Citation
Dessen P
RTKN (rhotekin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43808/rtkn-(rhotekin)
