Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6715
MIM: 184753
HGNC: 11284
Ensembl: ENSG00000145545
Variants:
dbSNP: 6715
ClinVar: 6715
TCGA: ENSG00000145545
COSMIC: SRD5A1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000145545 | ENST00000274192 | P18405 |
| ENSG00000145545 | ENST00000510531 | D6RDL6 |
| ENSG00000145545 | ENST00000513117 | D6RG03 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34996447 | 2022 | Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing. | 3 |
| 34996447 | 2022 | Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing. | 3 |
| 33627630 | 2021 | Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma. | 9 |
| 34764940 | 2021 | Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity. | 5 |
| 34885733 | 2021 | Treatment of Benign Prostatic Hyperplasia by Natural Drugs. | 24 |
| 33627630 | 2021 | Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma. | 9 |
| 34764940 | 2021 | Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity. | 5 |
| 34885733 | 2021 | Treatment of Benign Prostatic Hyperplasia by Natural Drugs. | 24 |
| 31870594 | 2020 | Associations of SRD5A1 gene variants and testosterone with dysglycemia: Henan Rural Cohort study. | 1 |
| 32716491 | 2020 | Expression in Escherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5α-Reductases. | 3 |
| 31870594 | 2020 | Associations of SRD5A1 gene variants and testosterone with dysglycemia: Henan Rural Cohort study. | 1 |
| 32716491 | 2020 | Expression in Escherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5α-Reductases. | 3 |
| 31199473 | 2019 | Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice. | 2 |
| 31199473 | 2019 | Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice. | 2 |
| 28347315 | 2017 | 5α-reductase activity in women with polycystic ovary syndrome: a systematic review and meta-analysis. | 15 |
Citation
Dessen P
SRD5A1 (steroid 5 alpha-reductase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43844/srd5a1-(steroid-5-alpha-reductase-1)
