RASSF8 (Ras association domain family member 8)

2007-02-01  

Identity

HGNC
RASSF8
LOCATION
12p12.1
LOCUSID
11228
ALIAS
C12orf2,HOJ1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11228
MIM: 608231
HGNC: 13232
Ensembl: ENSG00000123094

Variants:

dbSNP: 11228
ClinVar: 11228
TCGA: ENSG00000123094
COSMIC: RASSF8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123094ENST00000282884Q8NHQ8
ENSG00000123094ENST00000282884A0A024RB12
ENSG00000123094ENST00000381352Q8NHQ8
ENSG00000123094ENST00000405154Q8NHQ8
ENSG00000123094ENST00000405154A0A024RB12
ENSG00000123094ENST00000535907F5H8B9
ENSG00000123094ENST00000537946F5H343
ENSG00000123094ENST00000539545H0YG85
ENSG00000123094ENST00000541218F5H0S5
ENSG00000123094ENST00000541490Q8NHQ8
ENSG00000123094ENST00000541490A0A024RB12
ENSG00000123094ENST00000542004F5H7J1
ENSG00000123094ENST00000542315F5GYP8
ENSG00000123094ENST00000542865Q8NHQ8
ENSG00000123094ENST00000542865A0A024RB12
ENSG00000123094ENST00000545413F5H8C5
ENSG00000123094ENST00000611440Q6IB99
ENSG00000123094ENST00000615708Q8NHQ8

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
376012652023Tailored modulation of S100A1 and RASSF8 expression by butanediamide augments healing of rotator cuff tears.0
376012652023Tailored modulation of S100A1 and RASSF8 expression by butanediamide augments healing of rotator cuff tears.0
356765482022CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.4
358396102022RASSF8-AS1 displays low expression in colorectal cancer and up-regulates RASSF8 to suppress cell invasion and migration.3
356765482022CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.4
358396102022RASSF8-AS1 displays low expression in colorectal cancer and up-regulates RASSF8 to suppress cell invasion and migration.3
294672262018E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases.5
297260112018MiR-505 mediates methotrexate resistance in colorectal cancer by targeting RASSF8.10
294672262018E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases.5
297260112018MiR-505 mediates methotrexate resistance in colorectal cancer by targeting RASSF8.10
281738032017Hypoxia-inducible microRNA-224 promotes the cell growth, migration and invasion by directly targeting RASSF8 in gastric cancer.57
287709612017The miR-224 promotes non-small cell lung cancer cell proliferation by directly targeting RASSF8.16
281738032017Hypoxia-inducible microRNA-224 promotes the cell growth, migration and invasion by directly targeting RASSF8 in gastric cancer.57
287709612017The miR-224 promotes non-small cell lung cancer cell proliferation by directly targeting RASSF8.16
276269302016Over-Expressed miR-224 Promotes the Progression of Cervical Cancer via Targeting RASSF8.14

Citation

Dessen P

RASSF8 (Ras association domain family member 8)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43852/rassf8-(ras-association-domain-family-member-8)