Identity
HGNC
LOCATION
1p22.3
LOCUSID
ALIAS
Bif-1,CGI-61,PPP1R70,dJ612B15.2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51100
MIM: 609287
HGNC: 10833
Ensembl: ENSG00000097033
Variants:
dbSNP: 51100
ClinVar: 51100
TCGA: ENSG00000097033
COSMIC: SH3GLB1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Autophagy - animal | KEGG | ko04140 |
| Autophagy - animal | KEGG | hsa04140 |
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33086035 | 2021 | Amphipathic Motifs Regulate N-BAR Protein Endophilin B1 Auto-inhibition and Drive Membrane Remodeling. | 3 |
| 33086035 | 2021 | Amphipathic Motifs Regulate N-BAR Protein Endophilin B1 Auto-inhibition and Drive Membrane Remodeling. | 3 |
| 32493957 | 2020 | BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. | 6 |
| 33202207 | 2020 | Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. | 1 |
| 32493957 | 2020 | BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. | 6 |
| 33202207 | 2020 | Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. | 1 |
| 31126972 | 2019 | Bif-1 Interacts with Prohibitin-2 to Regulate Mitochondrial Inner Membrane during Cell Stress and Apoptosis. | 18 |
| 31126972 | 2019 | Bif-1 Interacts with Prohibitin-2 to Regulate Mitochondrial Inner Membrane during Cell Stress and Apoptosis. | 18 |
| 27112121 | 2016 | Endophilin B2 promotes inner mitochondrial membrane degradation by forming heterodimers with Endophilin B1 during mitophagy. | 7 |
| 27508440 | 2016 | Association of Endophilin B1 with Cytoplasmic Vesicles. | 8 |
| 27609472 | 2016 | Endophilin B1 regulates EGFR endocytic degradation in prostate cancer cell. | 3 |
| 27748942 | 2016 | Bax-interacting factor-1 inhibits cell proliferation and promotes apoptosis in prostate cancer cells. | 6 |
| 27112121 | 2016 | Endophilin B2 promotes inner mitochondrial membrane degradation by forming heterodimers with Endophilin B1 during mitophagy. | 7 |
| 27508440 | 2016 | Association of Endophilin B1 with Cytoplasmic Vesicles. | 8 |
| 27609472 | 2016 | Endophilin B1 regulates EGFR endocytic degradation in prostate cancer cell. | 3 |
Citation
Dessen P
SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43859/sh3glb1
