Identity
HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
GAA1,GPIBD15,hGAA1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8733
MIM: 603048
HGNC: 4446
Ensembl: ENSG00000197858
Variants:
dbSNP: 8733
ClinVar: 8733
TCGA: ENSG00000197858
COSMIC: GPAA1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33496978 | 2021 | Subunits of the GPI transamidase complex localize to the endoplasmic reticulum and nuclear envelope in Drosophila. | 2 |
| 33496978 | 2021 | Subunits of the GPI transamidase complex localize to the endoplasmic reticulum and nuclear envelope in Drosophila. | 2 |
| 32432756 | 2020 | GPAA1 promotes progression of childhood acute lymphoblastic leukemia through regulating c-myc. | 3 |
| 32533362 | 2020 | A novel variant in GPAA1, encoding a GPI transamidase complex protein, causes inherited vascular anomalies with various phenotypes. | 4 |
| 32993792 | 2020 | Structural modelling of the lumenal domain of human GPAA1, the metallo-peptide synthetase subunit of the transamidase complex, reveals zinc-binding mode and two flaps surrounding the active site. | 3 |
| 32432756 | 2020 | GPAA1 promotes progression of childhood acute lymphoblastic leukemia through regulating c-myc. | 3 |
| 32533362 | 2020 | A novel variant in GPAA1, encoding a GPI transamidase complex protein, causes inherited vascular anomalies with various phenotypes. | 4 |
| 32993792 | 2020 | Structural modelling of the lumenal domain of human GPAA1, the metallo-peptide synthetase subunit of the transamidase complex, reveals zinc-binding mode and two flaps surrounding the active site. | 3 |
| 31118109 | 2019 | GPAA1 promotes gastric cancer progression via upregulation of GPI-anchored protein and enhancement of ERBB signalling pathway. | 15 |
| 31118109 | 2019 | GPAA1 promotes gastric cancer progression via upregulation of GPI-anchored protein and enhancement of ERBB signalling pathway. | 15 |
| 29100095 | 2017 | Mutations in GPAA1, Encoding a GPI Transamidase Complex Protein, Cause Developmental Delay, Epilepsy, Cerebellar Atrophy, and Osteopenia. | 29 |
| 29100095 | 2017 | Mutations in GPAA1, Encoding a GPI Transamidase Complex Protein, Cause Developmental Delay, Epilepsy, Cerebellar Atrophy, and Osteopenia. | 29 |
| 24743167 | 2014 | Transamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein's omega-site and the GPI lipid anchor's phosphoethanolamine. | 22 |
| 24743167 | 2014 | Transamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein's omega-site and the GPI lipid anchor's phosphoethanolamine. | 22 |
| 18028549 | 2007 | Alterations of GPI transamidase subunits in head and neck squamous carcinoma. | 9 |
Citation
Dessen P
GPAA1 (glycosylphosphatidylinositol anchor attachment 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43871/gpaa1-(glycosylphosphatidylinositol-anchor-attachment-1)
