Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1535
MIM: 608508
HGNC: 2577
Ensembl: ENSG00000051523
Variants:
dbSNP: 1535
ClinVar: 1535
TCGA: ENSG00000051523
COSMIC: CYBA
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444516 | Hypercholesterolemia | Disease | ClinicalAnnotation | associated | PD | 15936011 | |
| PA445062 | Neoplasms | Disease | ClinicalAnnotation | associated | PD | 16330681, 19448608, 25823784, 28485375 | |
| PA449412 | doxorubicin | Chemical | ClinicalAnnotation, Pathway | associated | PD | 16330681, 19448608, 21048526, 25823784, 28485375 | |
| PA449961 | idarubicin | Chemical | ClinicalAnnotation | associated | PD | 16330681, 19448608, 25823784, 28485375 | |
| PA451363 | simvastatin | Chemical | ClinicalAnnotation | associated | PD | 15936011 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38355798 | 2024 | Structure of human phagocyte NADPH oxidase in the activated state. | 4 |
| 38355798 | 2024 | Structure of human phagocyte NADPH oxidase in the activated state. | 4 |
| 36606663 | 2023 | Characterization of missense mutations in the NADPH oxidase partner p22(phox) in the A22° subtype of chronic granulomatous disease. | 0 |
| 36626553 | 2023 | ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytes. | 2 |
| 37288802 | 2023 | CYBA allelic variants are associated with severity and recovery in Guillain-Barré syndrome. | 0 |
| 37643785 | 2023 | CYBA as a Potential Biomarker for Renal Cell Carcinoma: Evidence from an Integrated Genetic Analysis. | 0 |
| 36606663 | 2023 | Characterization of missense mutations in the NADPH oxidase partner p22(phox) in the A22° subtype of chronic granulomatous disease. | 0 |
| 36626553 | 2023 | ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytes. | 2 |
| 37288802 | 2023 | CYBA allelic variants are associated with severity and recovery in Guillain-Barré syndrome. | 0 |
| 37643785 | 2023 | CYBA as a Potential Biomarker for Renal Cell Carcinoma: Evidence from an Integrated Genetic Analysis. | 0 |
| 34825364 | 2022 | Association of CYBA C242T and superoxide dismutase 2 A16V genetic variants with preeclampsia. | 2 |
| 35073438 | 2022 | Impact of CYBA genotypes on severity and progression of multiple sclerosis. | 1 |
| 36421822 | 2022 | Polymorphic Variants of AGT, ABCA1, and CYBA Genes Influence the Survival of Patients with Coronary Artery Disease: A Prospective Cohort Study. | 2 |
| 34825364 | 2022 | Association of CYBA C242T and superoxide dismutase 2 A16V genetic variants with preeclampsia. | 2 |
| 35073438 | 2022 | Impact of CYBA genotypes on severity and progression of multiple sclerosis. | 1 |
Citation
Dessen P
CYBA (cytochrome b-245 alpha chain)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43882/cyba-(cytochrome-b-245-alpha-chain)
