Identity
HGNC
LOCATION
5p15.33
LOCUSID
ALIAS
CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT,hEST2,hTRT
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7015
MIM: 187270
HGNC: 11730
Ensembl: ENSG00000164362
Variants:
dbSNP: 7015
ClinVar: 7015
TCGA: ENSG00000164362
COSMIC: TERT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164362 | ENST00000310581 | O14746 |
| ENSG00000164362 | ENST00000334602 | O14746 |
| ENSG00000164362 | ENST00000460137 | O14746 |
| ENSG00000164362 | ENST00000656021 | A0A590UK92 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35153179 | 2024 | Differential immunohistochemical expression of hTERT in lung cancer patients with and without idiopathic pulmonary fibrosis. | 3 |
| 37771077 | 2024 | Role of gene sequencing in classifying struma ovarii: BRAF p.G469A mutation and TERT promoter alterations favour malignant struma ovarii. | 3 |
| 37857487 | 2024 | Telomerase reverse transcriptase gene polymorphisms and cervical cancer susceptibility in high-risk human papillomavirus-infected women. | 0 |
| 37926112 | 2024 | A rare homozygous variant in TERT gene causing variable bone marrow failure, fragility fractures, rib anomalies and extremely short telomere lengths with high serum IgE. | 0 |
| 38103361 | 2024 | TERT promoter mutations and the outcome of patients with advanced urothelial carcinoma treated by platinum-based chemotherapy or pembrolizumab. | 1 |
| 38113409 | 2024 | Genetic trio of BRAF and TERT alterations and rs2853669TT in papillary thyroid cancer aggressiveness. | 2 |
| 38134710 | 2024 | Identification of IDH and TERTp mutations using dynamic susceptibility contrast MRI with deep learning in 162 gliomas. | 1 |
| 38141254 | 2024 | Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression. | 1 |
| 38153178 | 2024 | Clinical, histological, and molecular differences in melanoma due to different TERT promoter mutations subtypes. A retrospective cross-sectional study in 684 melanoma patients. | 0 |
| 38184773 | 2024 | Association of Ultrasonography Features of Follicular Thyroid Carcinoma With Tumor Invasiveness and Prognosis Based on WHO Classification and TERT Promoter Mutation. | 1 |
| 38197421 | 2024 | Genetic association study of TERT gene variants with chronic kidney disease susceptibility in the Chinese population. | 0 |
| 38224873 | 2024 | TERT promoter mutations in atypical melanocytic lesions: A series of seven cases with adverse melanoma-specific outcome. | 0 |
| 38236501 | 2024 | TERT single nucleotide polymorphism rs2736098 but not rs2736100 is associated with telomere length in HIV-infected patients on cART. | 0 |
| 38278800 | 2024 | The regulations of telomerase reverse transcriptase (TERT) in cancer. | 4 |
| 38296486 | 2024 | Association of hTERT Gene Polymorphism and Colorectal Cancer (CRC) Risk in the Chinese Han Population. | 0 |
Citation
Dessen P
TERT (telomerase reverse transcriptase)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/439
