Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4776
MIM: 602699
HGNC: 7778
Ensembl: ENSG00000100968
Variants:
dbSNP: 4776
ClinVar: 4776
TCGA: ENSG00000100968
COSMIC: NFATC4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA33678 | PPP3CA | Gene | Pathway | associated | 23922006 | ||
| PA33679 | PPP3CB | Gene | Pathway | associated | 23922006 | ||
| PA33680 | PPP3CC | Gene | Pathway | associated | 23922006 | ||
| PA33681 | PPP3R1 | Gene | Pathway | associated | 23922006 | ||
| PA33682 | PPP3R2 | Gene | Pathway | associated | 23922006 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32182216 | 2020 | NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer. | 25 |
| 32805187 | 2020 | NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity. | 10 |
| 32182216 | 2020 | NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer. | 25 |
| 32805187 | 2020 | NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity. | 10 |
| 29180489 | 2018 | Downregulation of NFAT3 Due to Lack of T-Box Transcription Factor TBX5 Is Crucial for Cytokine Expression in T Cells. | 9 |
| 29180489 | 2018 | Downregulation of NFAT3 Due to Lack of T-Box Transcription Factor TBX5 Is Crucial for Cytokine Expression in T Cells. | 9 |
| 27893713 | 2017 | Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer. | 16 |
| 28760926 | 2017 | Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells. | 7 |
| 27893713 | 2017 | Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer. | 16 |
| 28760926 | 2017 | Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells. | 7 |
| 27307045 | 2016 | Neuritin Up-regulates Kv4.2 α-Subunit of Potassium Channel Expression and Affects Neuronal Excitability by Regulating the Calcium-Calcineurin-NFATc4 Signaling Pathway. | 17 |
| 27307045 | 2016 | Neuritin Up-regulates Kv4.2 α-Subunit of Potassium Channel Expression and Affects Neuronal Excitability by Regulating the Calcium-Calcineurin-NFATc4 Signaling Pathway. | 17 |
| 26527057 | 2015 | NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis. | 8 |
| 26527057 | 2015 | NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis. | 8 |
| 25422138 | 2014 | Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollagen I carboxyl terminal peptide and TGF-β1 levels in serum of patients with atrial fibrillation. | 5 |
Citation
Dessen P
NFATC4 (nuclear factor of activated T cells 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43963/nfatc4-(nuclear-factor-of-activated-t-cells-4)
