Identity
HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
CACNA2D,CASVDD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9254
MIM: 607082
HGNC: 1400
Ensembl: ENSG00000007402
Variants:
dbSNP: 9254
ClinVar: 9254
TCGA: ENSG00000007402
COSMIC: CACNA2D2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA448871 | celecoxib | Chemical | Pathway | associated | 22336956 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 25619833 | 2015 | CACNA2D2 promotes tumorigenesis by stimulating cell proliferation and angiogenesis. | 30 |
| 25619833 | 2015 | CACNA2D2 promotes tumorigenesis by stimulating cell proliferation and angiogenesis. | 30 |
| 23402298 | 2013 | Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects. | 10 |
| 23402298 | 2013 | Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects. | 10 |
| 21809394 | 2012 | Alterations of RASSF1A in premalignant cervical lesions: clinical and prognostic significance. | 4 |
| 21809394 | 2012 | Alterations of RASSF1A in premalignant cervical lesions: clinical and prognostic significance. | 4 |
| 17135419 | 2006 | The ducky(2J) mutation in Cacna2d2 results in reduced spontaneous Purkinje cell activity and altered gene expression. | 35 |
| 17135419 | 2006 | The ducky(2J) mutation in Cacna2d2 results in reduced spontaneous Purkinje cell activity and altered gene expression. | 35 |
| 15331424 | 2004 | Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene. | 47 |
| 15331424 | 2004 | Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene. | 47 |
| 12555074 | 2003 | CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity. | 32 |
| 12555074 | 2003 | CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity. | 32 |
| 11851383 | 2001 | Identification of a single nucleotide polymorphism in the human alpha 2 delta 2 calcium channel subunit gene. | 1 |
| 11851383 | 2001 | Identification of a single nucleotide polymorphism in the human alpha 2 delta 2 calcium channel subunit gene. | 1 |
Citation
Dessen P
CACNA2D2 (calcium voltage-gated channel auxiliary subunit alpha2delta 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43966/cacna2d2-(calcium-voltage-gated-channel-auxiliary-subunit-alpha2delta-2)
