LST1 (leukocyte specific transcript 1)

2007-02-01  

Identity

HGNC
LST1
LOCATION
6p21.33
LOCUSID
7940
ALIAS
B144,D6S49E,LST-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7940
MIM: 109170
HGNC: 14189
Ensembl: ENSG00000204482

Variants:

dbSNP: 7940
ClinVar: 7940
TCGA: ENSG00000204482
COSMIC: LST1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204482ENST00000211921Q5STB1
ENSG00000204482ENST00000376090Q5STB1
ENSG00000204482ENST00000376099Q5STB1
ENSG00000204482ENST00000396101Q2HNT4
ENSG00000204482ENST00000396112F2Z2M1
ENSG00000204482ENST00000433492Q5HYT5
ENSG00000204482ENST00000438075O00453
ENSG00000204482ENST00000438075A0A024RCT6
ENSG00000204482ENST00000464044H7C4M3
ENSG00000204482ENST00000490742H7C4Z3

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA443936Drug HypersensitivityDiseaseClinicalAnnotationassociatedPD
PA448004abacavirChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
367546762023Significance of leukocyte-specific transcript 1 levels in nasal mucosal tissue to predict recurrence of nasal polyps.0
367546762023Significance of leukocyte-specific transcript 1 levels in nasal mucosal tissue to predict recurrence of nasal polyps.0
300558632018LST1: A multifunctional gene encoded in the MHC class III region.2
300558632018LST1: A multifunctional gene encoded in the MHC class III region.2
273849232016Expression of ERAP2 and LST1 is increased before start of therapy in rheumatoid arthritis patients with good clinical response to glucocorticoids.4
273849232016Expression of ERAP2 and LST1 is increased before start of therapy in rheumatoid arthritis patients with good clinical response to glucocorticoids.4
246824112014Regulated expression of leukocyte-specific transcript (LST) 1 in human intestinal inflammation.11
248033362014Identification of functional haplotypes in the promoter region of the LST1 gene.1
248169912014An upstream open reading frame regulates LST1 expression during monocyte differentiation.4
246824112014Regulated expression of leukocyte-specific transcript (LST) 1 in human intestinal inflammation.11
248033362014Identification of functional haplotypes in the promoter region of the LST1 gene.1
248169912014An upstream open reading frame regulates LST1 expression during monocyte differentiation.4
232390252013LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation.73
232390252013LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation.73
225895432012LST1/A is a myeloid leukocyte-specific transmembrane adaptor protein recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to the plasma membrane.12

Citation

Dessen P

LST1 (leukocyte specific transcript 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43983/lst1-(leukocyte-specific-transcript-1)