Identity
HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
BP-4,HT29-IGFBP,IBP4,IGFBP-4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3487
MIM: 146733
HGNC: 5473
Ensembl: ENSG00000141753
Variants:
dbSNP: 3487
ClinVar: 3487
TCGA: ENSG00000141753
COSMIC: IGFBP4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000141753 | ENST00000269593 | P22692 |
| ENSG00000141753 | ENST00000269593 | A0A024R1U8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35971034 | 2023 | m(6)A mRNA methylation regulates the ERK/NF-κB/AKT signaling pathway through the PAPPA/IGFBP4 axis to promote proliferation and tumor formation in endometrial cancer. | 5 |
| 37176126 | 2023 | PAPP-A-Specific IGFBP-4 Proteolysis in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. | 0 |
| 37433992 | 2023 | The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4. | 1 |
| 37605556 | 2023 | AKAP12 and IGFBP4 Are Prognostic Factors for Chronic Lymphocytic Leukemia. | 0 |
| 37762544 | 2023 | Increased Levels of Circulating IGFBP4 and ANGPTL8 with a Prospective Role in Diabetic Nephropathy. | 2 |
| 35971034 | 2023 | m(6)A mRNA methylation regulates the ERK/NF-κB/AKT signaling pathway through the PAPPA/IGFBP4 axis to promote proliferation and tumor formation in endometrial cancer. | 5 |
| 37176126 | 2023 | PAPP-A-Specific IGFBP-4 Proteolysis in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. | 0 |
| 37433992 | 2023 | The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4. | 1 |
| 37605556 | 2023 | AKAP12 and IGFBP4 Are Prognostic Factors for Chronic Lymphocytic Leukemia. | 0 |
| 37762544 | 2023 | Increased Levels of Circulating IGFBP4 and ANGPTL8 with a Prospective Role in Diabetic Nephropathy. | 2 |
| 35588861 | 2022 | Increased activity of the metalloproteinase PAPP-A promotes diabetes-induced glomerular hypertrophy. | 3 |
| 35688891 | 2022 | Functional characterization of a novel p.Ser76Thr variant in IGFBP4 that associates with body mass index in American Indians. | 1 |
| 36203260 | 2022 | Exosome-associated microRNA-375 induces cell proliferation by regulating IGFBP4 upon hepatitis C virus infection. | 2 |
| 35588861 | 2022 | Increased activity of the metalloproteinase PAPP-A promotes diabetes-induced glomerular hypertrophy. | 3 |
| 35688891 | 2022 | Functional characterization of a novel p.Ser76Thr variant in IGFBP4 that associates with body mass index in American Indians. | 1 |
Citation
Dessen P
IGFBP4 (insulin like growth factor binding protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43990/igfbp4-(insulin-like-growth-factor-binding-protein-4)
