Identity
HGNC
LOCATION
7q36.1
LOCUSID
ALIAS
AE2,BND3L,EPB3L1,HKB3,NBND3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6522
MIM: 109280
HGNC: 11028
Ensembl: ENSG00000164889
Variants:
dbSNP: 6522
ClinVar: 6522
TCGA: ENSG00000164889
COSMIC: SLC4A2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36343920 | 2023 | SLC4A2, another gene involved in acid-base balancing machinery of osteoclasts, causes osteopetrosis. | 2 |
| 37270778 | 2023 | Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2. | 3 |
| 36343920 | 2023 | SLC4A2, another gene involved in acid-base balancing machinery of osteoclasts, causes osteopetrosis. | 2 |
| 37270778 | 2023 | Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2. | 3 |
| 33727633 | 2021 | Both IRBIT and long-IRBIT bind to and coordinately regulate Cl(-)/HCO(3)(-) exchanger AE2 activity through modulating the lysosomal degradation of AE2. | 3 |
| 34279699 | 2021 | SLC4A2 anion exchanger promotes tumour cell malignancy via enhancing net acid efflux across golgi membranes. | 6 |
| 34944008 | 2021 | Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid-Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario. | 5 |
| 33727633 | 2021 | Both IRBIT and long-IRBIT bind to and coordinately regulate Cl(-)/HCO(3)(-) exchanger AE2 activity through modulating the lysosomal degradation of AE2. | 3 |
| 34279699 | 2021 | SLC4A2 anion exchanger promotes tumour cell malignancy via enhancing net acid efflux across golgi membranes. | 6 |
| 34944008 | 2021 | Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid-Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario. | 5 |
| 33182643 | 2020 | Intracellular Ca(2+)-Mediated AE2 Is Involved in the Vectorial Movement of HaCaT Keratinocyte. | 8 |
| 33182643 | 2020 | Intracellular Ca(2+)-Mediated AE2 Is Involved in the Vectorial Movement of HaCaT Keratinocyte. | 8 |
| 28455748 | 2017 | CK2 is a key regulator of SLC4A2-mediated Cl(-)/HCO(3)(-) exchange in human airway epithelia. | 7 |
| 28743911 | 2017 | Knockdown of anion exchanger 2 suppressed the growth of ovarian cancer cells via mTOR/p70S6K1 signaling. | 10 |
| 28455748 | 2017 | CK2 is a key regulator of SLC4A2-mediated Cl(-)/HCO(3)(-) exchange in human airway epithelia. | 7 |
Citation
Dessen P
SLC4A2 (solute carrier family 4 member 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43994
