Identity
HGNC
LOCATION
3q29
LOCUSID
ALIAS
ACK,ACK-1,ACK1,p21cdc42Hs
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10188
MIM: 606994
HGNC: 19297
Ensembl: ENSG00000061938
Variants:
dbSNP: 10188
ClinVar: 10188
TCGA: ENSG00000061938
COSMIC: TNK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000061938 | ENST00000333602 | Q07912 |
| ENSG00000061938 | ENST00000381916 | A0A499FJ16 |
| ENSG00000061938 | ENST00000428187 | C9J1X3 |
| ENSG00000061938 | ENST00000439230 | Q07912 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38650011 | 2024 | ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway. | 1 |
| 38650011 | 2024 | ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway. | 1 |
| 36773333 | 2023 | Activation of E3 ubiquitin ligase WWP2 by non-receptor tyrosine kinase ACK1. | 1 |
| 36854171 | 2023 | Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk. | 0 |
| 36980241 | 2023 | Domain Architecture of the Nonreceptor Tyrosine Kinase Ack1. | 1 |
| 37133719 | 2023 | Host factor TNK2 is required for influenza virus infection. | 1 |
| 37194323 | 2023 | ACKnowledging the role of the Activated-Cdc42 associated kinase (ACK) in regulating protein stability in cancer. | 1 |
| 36773333 | 2023 | Activation of E3 ubiquitin ligase WWP2 by non-receptor tyrosine kinase ACK1. | 1 |
| 36854171 | 2023 | Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk. | 0 |
| 36980241 | 2023 | Domain Architecture of the Nonreceptor Tyrosine Kinase Ack1. | 1 |
| 37133719 | 2023 | Host factor TNK2 is required for influenza virus infection. | 1 |
| 37194323 | 2023 | ACKnowledging the role of the Activated-Cdc42 associated kinase (ACK) in regulating protein stability in cancer. | 1 |
| 35429500 | 2022 | Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK. | 7 |
| 36178070 | 2022 | Activity of the nonreceptor tyrosine kinase Ack1 is regulated by tyrosine phosphorylation of its Mig6 homology region. | 3 |
| 35429500 | 2022 | Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK. | 7 |
Citation
Dessen P
TNK2 (tyrosine kinase non receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/44030/tnk2-(tyrosine-kinase-non-receptor-2)
