HOXC6 (homeobox C6)

2007-06-01  

Identity

HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
CP25,HHO.C8,HOX3,HOX3C
FUSION GENES

Other Information

Locus ID:

NCBI: 3223
MIM: 142972
HGNC: 5128
Ensembl: ENSG00000197757

Variants:

dbSNP: 3223
ClinVar: 3223
TCGA: ENSG00000197757
COSMIC: HOXC6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197757ENST00000243108P09630
ENSG00000197757ENST00000394331P09630
ENSG00000197757ENST00000504315D6RBH4
ENSG00000197757ENST00000509328D6RC34

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

References

Pubmed IDYearTitleCitations
271081622016Detection of High-grade Prostate Cancer Using a Urinary Molecular Biomarker-Based Risk Score.52
156375922005Loss of HOXC6 expression induces apoptosis in prostate cancer cells.34
216830832011HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.34
275749492016Long Noncoding RNA HOXC-AS1 Suppresses Ox-LDL-Induced Cholesterol Accumulation Through Promoting HOXC6 Expression in THP-1 Macrophages.16
174884782007HOXC6 and HOXC11 increase transcription of S100beta gene in BrdU-induced in vitro differentiation of GOTO neuroblastoma cells into Schwannian cells.14
245250582014The survival predictive significance of HOXC6 and HOXC8 in esophageal squamous cell carcinoma.14
263108142015The role of HOXC6 in prostate cancer development.14
235814172013Upregulated Hoxc6 expression is associated with poor survival in gastric cancer patients.11
257254832015Bisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer.11
228967032012HOXC6 is deregulated in human head and neck squamous cell carcinoma and modulates Bcl-2 expression.10

Citation

Dessen P

HOXC6 (homeobox C6)

Atlas Genet Cytogenet Oncol Haematol. 2007-06-01

Online version: http://atlasgeneticsoncology.org/gene/44032/hoxc6-(homeobox-c6)