ZNF521 (zinc finger protein 521)

2007-06-01  

Identity

HGNC
LOCATION
18q11.2
LOCUSID
ALIAS
EHZF,Evi3
FUSION GENES

Other Information

Locus ID:

NCBI: 25925
MIM: 610974
HGNC: 24605
Ensembl: ENSG00000198795

Variants:

dbSNP: 25925
ClinVar: 25925
TCGA: ENSG00000198795
COSMIC: ZNF521

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198795ENST00000361524Q96K83
ENSG00000198795ENST00000399425H7BYU6
ENSG00000198795ENST00000538137Q96K83
ENSG00000198795ENST00000577461J3KT07
ENSG00000198795ENST00000577775J3QQI2
ENSG00000198795ENST00000577801J3KSZ4
ENSG00000198795ENST00000580488J3QRW6
ENSG00000198795ENST00000584787J3KTI4

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
146307872004Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells.38
175435732008Early hematopoietic zinc finger protein-zinc finger protein 521: a candidate regulator of diverse immature cells.27
215935902011Zinc finger protein 521 antagonizes early B-cell factor 1 and modulates the B-lymphoid differentiation of primary hematopoietic progenitors.24
203922152010Zinc finger protein 521, a new player in bone formation.17
239075692013Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells.16
190499732009The role of zinc finger protein 521/early hematopoietic zinc finger protein in erythroid cell differentiation.15
193426262009Early hematopoietic zinc finger protein prevents tumor cell recognition by natural killer cells.10
267884972015ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies.10
278050022016Performance Metrics for Selecting Single Nucleotide Polymorphisms in Late-onset Alzheimer's Disease.8
299383522018ZNF521 Has an Inhibitory Effect on the Adipogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells.8

Citation

Dessen P

ZNF521 (zinc finger protein 521)

Atlas Genet Cytogenet Oncol Haematol. 2007-06-01

Online version: http://atlasgeneticsoncology.org/gene/44033/znf521-(zinc-finger-protein-521)