Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7297
MIM: 176941
HGNC: 12440
Ensembl: ENSG00000105397
Variants:
dbSNP: 7297
ClinVar: 7297
TCGA: ENSG00000105397
COSMIC: TYK2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37950407 | 2024 | Community analysis of large-scale molecular dynamics simulations elucidated dynamics-driven allostery in tyrosine kinase 2. | 0 |
| 38337161 | 2024 | Associations of genetic variants within TYK2 with pulmonary tuberculosis among Chinese population. | 1 |
| 37950407 | 2024 | Community analysis of large-scale molecular dynamics simulations elucidated dynamics-driven allostery in tyrosine kinase 2. | 0 |
| 38337161 | 2024 | Associations of genetic variants within TYK2 with pulmonary tuberculosis among Chinese population. | 1 |
| 36519621 | 2023 | Clinical Implications of Targeting the JAK-STAT Pathway in Psoriatic Disease: Emphasis on the TYK2 Pathway. | 6 |
| 36781502 | 2023 | The positive feedback loop of MAD2L1/TYK2/STAT3 induces progression in B-cell acute lymphoblastic leukaemia. | 0 |
| 36834806 | 2023 | Tyk2 Targeting in Immune-Mediated Inflammatory Diseases. | 17 |
| 36959416 | 2023 | TYK2 single-nucleotide variants associated with the severity of COVID-19 disease. | 2 |
| 37860832 | 2023 | Tick-borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2. | 1 |
| 37983265 | 2023 | Direct and biologically significant interactions of human herpesvirus 8 interferon regulatory factor 1 with STAT3 and Janus kinase TYK2. | 3 |
| 36519621 | 2023 | Clinical Implications of Targeting the JAK-STAT Pathway in Psoriatic Disease: Emphasis on the TYK2 Pathway. | 6 |
| 36781502 | 2023 | The positive feedback loop of MAD2L1/TYK2/STAT3 induces progression in B-cell acute lymphoblastic leukaemia. | 0 |
| 36834806 | 2023 | Tyk2 Targeting in Immune-Mediated Inflammatory Diseases. | 17 |
| 36959416 | 2023 | TYK2 single-nucleotide variants associated with the severity of COVID-19 disease. | 2 |
| 37860832 | 2023 | Tick-borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2. | 1 |
Citation
Dessen P
TYK2 (tyrosine kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/446/tyk2
