Identity
HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
HUMORFA01,SAR1,p195
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8826
MIM: 603379
HGNC: 6110
Ensembl: ENSG00000140575
Variants:
dbSNP: 8826
ClinVar: 8826
TCGA: ENSG00000140575
COSMIC: IQGAP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38424547 | 2024 | Tight junction protein cingulin variant is associated with cancer susceptibility by overexpressed IQGAP1 and Rac1-dependent epithelial-mesenchymal transition. | 1 |
| 38536816 | 2024 | IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF. | 0 |
| 38787349 | 2024 | Coordination of actin plus-end dynamics by IQGAP1, formin, and capping protein. | 0 |
| 38834690 | 2024 | In silico predicted compound targeting the IQGAP1-GRD domain selectively inhibits growth of human acute myeloid leukemia. | 0 |
| 38943117 | 2024 | Deciphering the SOX4/MAPK1 regulatory axis: a phosphoproteomic insight into IQGAP1 phosphorylation and pancreatic Cancer progression. | 0 |
| 38424547 | 2024 | Tight junction protein cingulin variant is associated with cancer susceptibility by overexpressed IQGAP1 and Rac1-dependent epithelial-mesenchymal transition. | 1 |
| 38536816 | 2024 | IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF. | 0 |
| 38787349 | 2024 | Coordination of actin plus-end dynamics by IQGAP1, formin, and capping protein. | 0 |
| 38834690 | 2024 | In silico predicted compound targeting the IQGAP1-GRD domain selectively inhibits growth of human acute myeloid leukemia. | 0 |
| 38943117 | 2024 | Deciphering the SOX4/MAPK1 regulatory axis: a phosphoproteomic insight into IQGAP1 phosphorylation and pancreatic Cancer progression. | 0 |
| 37071417 | 2023 | The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling. | 5 |
| 37373423 | 2023 | 7-Ketocholesterol Promotes Retinal Pigment Epithelium Senescence and Fibrosis of Choroidal Neovascularization via IQGAP1 Phosphorylation-Dependent Signaling. | 2 |
| 37597406 | 2023 | IQGAP1 promotes mitochondrial damage and activation of the mtDNA sensor cGAS-STING pathway to induce endothelial cell pyroptosis leading to atherosclerosis. | 5 |
| 37071417 | 2023 | The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling. | 5 |
| 37373423 | 2023 | 7-Ketocholesterol Promotes Retinal Pigment Epithelium Senescence and Fibrosis of Choroidal Neovascularization via IQGAP1 Phosphorylation-Dependent Signaling. | 2 |
Citation
Dessen P
IQGAP1 (IQ motif containing GTPase activating protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2005-02-01
Online version: http://atlasgeneticsoncology.org/gene/45512/iqgap1-(iq-motif-containing-gtpase-activating-protein-1)
