Identity
HGNC
LOCATION
12p12.1
LOCUSID
ALIAS
GD3S,SIAT8,SIAT8-A,SIAT8A,ST8SiaI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6489
MIM: 601123
HGNC: 10869
Ensembl: ENSG00000111728
Variants:
dbSNP: 6489
ClinVar: 6489
TCGA: ENSG00000111728
COSMIC: ST8SIA1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36897478 | 2023 | Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells. | 1 |
| 37554309 | 2023 | The yes-associated protein (YAP) is associated with resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of ST8SIA1. | 3 |
| 36897478 | 2023 | Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells. | 1 |
| 37554309 | 2023 | The yes-associated protein (YAP) is associated with resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of ST8SIA1. | 3 |
| 34160287 | 2022 | BACH1 Binding Links the Genetic Risk for Severe Periodontitis with ST8SIA1. | 4 |
| 34160287 | 2022 | BACH1 Binding Links the Genetic Risk for Severe Periodontitis with ST8SIA1. | 4 |
| 32939659 | 2021 | ST8SIA1 inhibition sensitizes triple negative breast cancer to chemotherapy via suppressing Wnt/β-catenin and FAK/Akt/mTOR. | 17 |
| 33846784 | 2021 | Knockdown of lncRNA MIR4435‑2HG and ST8SIA1 expression inhibits the proliferation, invasion and migration of prostate cancer cells in vitro and in vivo by blocking the activation of the FAK/AKT/β‑catenin signaling pathway. | 22 |
| 34738863 | 2021 | Long noncoding RNA NR2F1-AS1 plays a carcinogenic role in gastric cancer by recruiting transcriptional factor SPI1 to upregulate ST8SIA1 expression. | 9 |
| 32939659 | 2021 | ST8SIA1 inhibition sensitizes triple negative breast cancer to chemotherapy via suppressing Wnt/β-catenin and FAK/Akt/mTOR. | 17 |
| 33846784 | 2021 | Knockdown of lncRNA MIR4435‑2HG and ST8SIA1 expression inhibits the proliferation, invasion and migration of prostate cancer cells in vitro and in vivo by blocking the activation of the FAK/AKT/β‑catenin signaling pathway. | 22 |
| 34738863 | 2021 | Long noncoding RNA NR2F1-AS1 plays a carcinogenic role in gastric cancer by recruiting transcriptional factor SPI1 to upregulate ST8SIA1 expression. | 9 |
| 33260650 | 2020 | Comprehensive Transcriptomic Analysis Identifies ST8SIA1 as a Survival-Related Sialyltransferase Gene in Breast Cancer. | 6 |
| 33260650 | 2020 | Comprehensive Transcriptomic Analysis Identifies ST8SIA1 as a Survival-Related Sialyltransferase Gene in Breast Cancer. | 6 |
| 31537151 | 2019 | Smoking Modifies the Genetic Risk for Early-Onset Periodontitis. | 11 |
Citation
Dessen P
ST8SIA1 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45520/st8sia1-(st8-alpha-n-acetyl-neuraminide-alpha-2-8-sialyltransferase-1)
