Identity
HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
MAC30,sigma2R
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27346
MIM: 612912
HGNC: 28106
Ensembl: ENSG00000109084
Variants:
dbSNP: 27346
ClinVar: 27346
TCGA: ENSG00000109084
COSMIC: TMEM97
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38319380 | 2024 | Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease. | 0 |
| 38388887 | 2024 | TMEM97 knockdown inhibits 5-fluorouracil resistance by regulating epithelial-mesenchymal transition and ABC transporter expression via inactivating the Akt/mTOR pathway in 5-fluorouracil-resistant colorectal cancer cells. | 0 |
| 38319380 | 2024 | Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease. | 0 |
| 38388887 | 2024 | TMEM97 knockdown inhibits 5-fluorouracil resistance by regulating epithelial-mesenchymal transition and ABC transporter expression via inactivating the Akt/mTOR pathway in 5-fluorouracil-resistant colorectal cancer cells. | 0 |
| 37047353 | 2023 | Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97. | 3 |
| 37047353 | 2023 | Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97. | 3 |
| 35373413 | 2022 | Inhibition of MAC30 exerts antitumor effects in nasopharyngeal carcinoma via affecting the Akt/GSK-3β/β-catenin pathway. | 2 |
| 35907137 | 2022 | TMEM97 is transcriptionally activated by YY1 and promotes colorectal cancer progression via the GSK-3β/β-catenin signaling pathway. | 4 |
| 35970844 | 2022 | GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and -activating properties of human salivary histatin 1. | 2 |
| 35373413 | 2022 | Inhibition of MAC30 exerts antitumor effects in nasopharyngeal carcinoma via affecting the Akt/GSK-3β/β-catenin pathway. | 2 |
| 35907137 | 2022 | TMEM97 is transcriptionally activated by YY1 and promotes colorectal cancer progression via the GSK-3β/β-catenin signaling pathway. | 4 |
| 35970844 | 2022 | GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and -activating properties of human salivary histatin 1. | 2 |
| 33618021 | 2021 | TMEM97 facilitates the activation of SOCE by downregulating the association of cholesterol to Orai1 in MDA-MB-231 cells. | 6 |
| 34233061 | 2021 | Histatin-1 is an endogenous ligand of the sigma-2 receptor. | 4 |
| 34615853 | 2021 | Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer. | 6 |
Citation
Dessen P
TMEM97 (transmembrane protein 97)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45539/tmem97-(transmembrane-protein-97)
