ARID3A (AT-rich interaction domain 3A)

2007-02-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
BRIGHT,DRIL1,DRIL3,E2FBP1
FUSION GENES

Other Information

Locus ID:

NCBI: 1820
MIM: 603265
HGNC: 3031
Ensembl: ENSG00000116017

Variants:

dbSNP: 1820
ClinVar: 1820
TCGA: ENSG00000116017
COSMIC: ARID3A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116017ENST00000263620Q99856
ENSG00000116017ENST00000457152H0YFY1
ENSG00000116017ENST00000587532K7EJ04

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
TP53 Regulates Transcription of Cell Cycle GenesREACTOMER-HSA-6791312
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle ArrestREACTOMER-HSA-6804116

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
363013682023Several genetic variants associated with systemic sclerosis in a Chinese Han population.1
369776692023A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression.1
363013682023Several genetic variants associated with systemic sclerosis in a Chinese Han population.1
369776692023A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression.1
345708852022The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis.17
352190692022MiR-361-3p promotes tumorigenesis of osteosarcoma cells via targeting ARID3A.2
352574282022ARID3A promotes the chemosensitivity of colon cancer by inhibiting AKR1C3.2
360083832022Hepatic ARID3A facilitates liver cancer malignancy by cooperating with CEP131 to regulate an embryonic stem cell-like gene signature.4
345708852022The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis.17
352190692022MiR-361-3p promotes tumorigenesis of osteosarcoma cells via targeting ARID3A.2
352574282022ARID3A promotes the chemosensitivity of colon cancer by inhibiting AKR1C3.2
360083832022Hepatic ARID3A facilitates liver cancer malignancy by cooperating with CEP131 to regulate an embryonic stem cell-like gene signature.4
331655752021ARID3A promotes the development of colorectal cancer by upregulating AURKA.21
336498632021Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes.3
346635942021Deficiencies in the DNA Binding Protein ARID3a Alter Chromatin Structures Important for Early Human Erythropoiesis.0

Citation

Dessen P

ARID3A (AT-rich interaction domain 3A)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45573/arid3a-(at-rich-interaction-domain-3a)