Identity
HGNC
LOCATION
8p11.23
LOCUSID
ALIAS
GPR124,TEM5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25960
MIM: 606823
HGNC: 17849
Ensembl: ENSG00000020181
Variants:
dbSNP: 25960
ClinVar: 25960
TCGA: ENSG00000020181
COSMIC: ADGRA2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000020181 | ENST00000315215 | Q96PE1 |
| ENSG00000020181 | ENST00000412232 | Q96PE1 |
| ENSG00000020181 | ENST00000428068 | H7C1L1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37694534 | 2024 | Down-regulated Wnt7a and GPR124 in early-onset preeclampsia placentas reduce invasion and migration of trophoblast cells. | 0 |
| 37694534 | 2024 | Down-regulated Wnt7a and GPR124 in early-onset preeclampsia placentas reduce invasion and migration of trophoblast cells. | 0 |
| 35649360 | 2022 | An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates. | 5 |
| 35649360 | 2022 | An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates. | 5 |
| 32991049 | 2021 | Variants of WNT7A and GPR124 are associated with hemorrhagic transformation following intravenous thrombolysis in ischemic stroke. | 11 |
| 32991049 | 2021 | Variants of WNT7A and GPR124 are associated with hemorrhagic transformation following intravenous thrombolysis in ischemic stroke. | 11 |
| 31058365 | 2019 | GPR124 regulates microtubule assembly, mitotic progression, and glioblastoma cell proliferation. | 10 |
| 31352222 | 2019 | Serum TEM5 and TEM7 concentrations correlate with clinicopathologic features and poor prognosis of colorectal cancer patients. | 5 |
| 31058365 | 2019 | GPR124 regulates microtubule assembly, mitotic progression, and glioblastoma cell proliferation. | 10 |
| 31352222 | 2019 | Serum TEM5 and TEM7 concentrations correlate with clinicopathologic features and poor prognosis of colorectal cancer patients. | 5 |
| 28600358 | 2017 | Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock. | 14 |
| 28600358 | 2017 | Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock. | 14 |
| 24582749 | 2014 | miR-138-5p reverses gefitinib resistance in non-small cell lung cancer cells via negatively regulating G protein-coupled receptor 124. | 60 |
| 24582749 | 2014 | miR-138-5p reverses gefitinib resistance in non-small cell lung cancer cells via negatively regulating G protein-coupled receptor 124. | 60 |
| 22013897 | 2012 | Thrombin-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein disulfide-isomerase. | 9 |
Citation
Dessen P
ADGRA2 (adhesion G protein-coupled receptor A2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45576/adgra2-(adhesion-g-protein-coupled-receptor-a2)
