Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 916
MIM: 186830
HGNC: 1674
Ensembl: ENSG00000198851
Variants:
dbSNP: 916
ClinVar: 916
TCGA: ENSG00000198851
COSMIC: CD3E
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198851 | ENST00000361763 | P07766 |
| ENSG00000198851 | ENST00000528600 | E9PSH8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35710869 | 2022 | Low transcriptomic of PTPRCv1 and CD3E is an independent predictor of mortality in HIV and tuberculosis co-infected patient. | 0 |
| 35710869 | 2022 | Low transcriptomic of PTPRCv1 and CD3E is an independent predictor of mortality in HIV and tuberculosis co-infected patient. | 0 |
| 31674657 | 2020 | Actin polymerization regulates recruitment of Nck to CD3ε upon T-cell receptor triggering. | 5 |
| 32016651 | 2020 | Biallelic Form of a Known CD3E Mutation in a Patient with Severe Combined Immunodeficiency. | 4 |
| 32730808 | 2020 | Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy. | 65 |
| 31674657 | 2020 | Actin polymerization regulates recruitment of Nck to CD3ε upon T-cell receptor triggering. | 5 |
| 32016651 | 2020 | Biallelic Form of a Known CD3E Mutation in a Patient with Severe Combined Immunodeficiency. | 4 |
| 32730808 | 2020 | Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy. | 65 |
| 28597365 | 2017 | A novel pathogenic frameshift variant of CD3E gene in two T-B+ NK+ SCID patients from Turkey. | 7 |
| 28659468 | 2017 | Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling. | 49 |
| 28597365 | 2017 | A novel pathogenic frameshift variant of CD3E gene in two T-B+ NK+ SCID patients from Turkey. | 7 |
| 28659468 | 2017 | Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling. | 49 |
| 26828096 | 2016 | The Transmembrane Domain of HIV-1 gp41 Inhibits T-Cell Activation by Targeting Multiple T-Cell Receptor Complex Components through Its GxxxG Motif. | 10 |
| 26888626 | 2016 | Change in CD3ζ-chain expression is an independent predictor of disease status in head and neck cancer patients. | 11 |
| 27754869 | 2016 | The Stalk Domain of NKp30 Contributes to Ligand Binding and Signaling of a Preassembled NKp30-CD3ζ Complex. | 6 |
Citation
Dessen P
CD3E (CD3e molecule)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45585/cd3e-(cd3e-molecule)
