Identity
HGNC
LOCATION
12q24.11
LOCUSID
ALIAS
CAT-2,CAT2,PKL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9815
MIM: 608564
HGNC: 4273
Ensembl: ENSG00000139436
Variants:
dbSNP: 9815
ClinVar: 9815
TCGA: ENSG00000139436
COSMIC: GIT2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37156999 | 2023 | Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries. | 28 |
| 37156999 | 2023 | Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries. | 28 |
| 32743695 | 2020 | Long non-coding RNA MALAT1 promotes odontogenic differentiation of human dental pulp stem cells by impairing microRNA-140-5p-dependent downregulation of GIT2. | 8 |
| 32743695 | 2020 | Long non-coding RNA MALAT1 promotes odontogenic differentiation of human dental pulp stem cells by impairing microRNA-140-5p-dependent downregulation of GIT2. | 8 |
| 30915469 | 2019 | GIT2 deficiency attenuates inflammation-induced expression of pro-labor mediators in human amnion and myometrial cells†. | 2 |
| 30915469 | 2019 | GIT2 deficiency attenuates inflammation-induced expression of pro-labor mediators in human amnion and myometrial cells†. | 2 |
| 27669437 | 2017 | The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. | 19 |
| 27669437 | 2017 | The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. | 19 |
| 27182061 | 2016 | Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes. | 63 |
| 27238570 | 2016 | EGF-stimulated activation of Rab35 regulates RUSC2-GIT2 complex formation to stabilize GIT2 during directional lung cancer cell migration. | 19 |
| 27182061 | 2016 | Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes. | 63 |
| 27238570 | 2016 | EGF-stimulated activation of Rab35 regulates RUSC2-GIT2 complex formation to stabilize GIT2 during directional lung cancer cell migration. | 19 |
| 25605334 | 2015 | Nuclear GIT2 is an ATM substrate and promotes DNA repair. | 17 |
| 25605334 | 2015 | Nuclear GIT2 is an ATM substrate and promotes DNA repair. | 17 |
| 23591815 | 2013 | Loss of Git2 induces epithelial-mesenchymal transition by miR146a-Cnot6L-controlled expression of Zeb1. | 7 |
Citation
Dessen P
GIT2 (GIT ArfGAP 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45589/git2-(git-arfgap-2)
