Identity
HGNC
LOCATION
6p22.2
LOCUSID
ALIAS
CALBL,DJ501N12.8,SECRET,SEGN,setagin
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10590
MIM: 609202
HGNC: 16941
Ensembl: ENSG00000079689
Variants:
dbSNP: 10590
ClinVar: 10590
TCGA: ENSG00000079689
COSMIC: SCGN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000079689 | ENST00000334979 | Q96P10 |
| ENSG00000079689 | ENST00000377961 | O76038 |
| ENSG00000079689 | ENST00000612225 | Q96P10 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36588101 | 2023 | SCGN deficiency is a risk factor for autism spectrum disorder. | 9 |
| 36588101 | 2023 | SCGN deficiency is a risk factor for autism spectrum disorder. | 9 |
| 31512254 | 2020 | Differential expression of secretagogin immunostaining in the hippocampal formation and the entorhinal and perirhinal cortices of humans, rats, and mice. | 10 |
| 31512254 | 2020 | Differential expression of secretagogin immunostaining in the hippocampal formation and the entorhinal and perirhinal cortices of humans, rats, and mice. | 10 |
| 31663849 | 2019 | SCGN deficiency results in colitis susceptibility. | 12 |
| 31663849 | 2019 | SCGN deficiency results in colitis susceptibility. | 12 |
| 29499408 | 2018 | Overexpression of secretagogin promotes cell apoptosis and inhibits migration and invasion of human SW480 human colorectal cancer cells. | 2 |
| 29702679 | 2018 | Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction. | 7 |
| 29499408 | 2018 | Overexpression of secretagogin promotes cell apoptosis and inhibits migration and invasion of human SW480 human colorectal cancer cells. | 2 |
| 29702679 | 2018 | Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction. | 7 |
| 28223495 | 2017 | Secretagogin-dependent matrix metalloprotease-2 release from neurons regulates neuroblast migration. | 16 |
| 28325894 | 2017 | SUMOylation and calcium control syntaxin-1A and secretagogin sequestration by tomosyn to regulate insulin exocytosis in human ß cells. | 23 |
| 28492151 | 2017 | Secretagogin (SCGN) Plasma Levels and their Association with Cognitive and Social Behavior in Children with Autism Spectrum Disorder ASD). | 3 |
| 28637794 | 2017 | A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover. | 32 |
| 28223495 | 2017 | Secretagogin-dependent matrix metalloprotease-2 release from neurons regulates neuroblast migration. | 16 |
Citation
Dessen P
SCGN (secretagogin, EF-hand calcium binding protein)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45603/scgn-(secretagogin-ef-hand-calcium-binding-protein)
