Identity
HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
CDC91L1,GAB1,GPIBD21,NEDBSS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 128869
MIM: 608528
HGNC: 15791
Ensembl: ENSG00000101464
Variants:
dbSNP: 128869
ClinVar: 128869
TCGA: ENSG00000101464
COSMIC: PIGU
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101464 | ENST00000217446 | Q9H490 |
| ENSG00000101464 | ENST00000374820 | Q9H490 |
| ENSG00000101464 | ENST00000438215 | Q5JWU1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34576938 | 2021 | Functional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit. | 5 |
| 34576938 | 2021 | Functional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit. | 5 |
| 32552000 | 2020 | Identification of PIGU as the Hub Gene Associated with KRAS Mutation in Colorectal Cancer by Coexpression Analysis. | 4 |
| 32971102 | 2020 | PIGU promotes hepatocellular carcinoma progression through activating NF-κB pathway and increasing immune escape. | 7 |
| 32552000 | 2020 | Identification of PIGU as the Hub Gene Associated with KRAS Mutation in Colorectal Cancer by Coexpression Analysis. | 4 |
| 32971102 | 2020 | PIGU promotes hepatocellular carcinoma progression through activating NF-κB pathway and increasing immune escape. | 7 |
| 30171988 | 2019 | PIGU overexpression adds value to TNM staging in the prognostic stratification of patients with hepatocellular carcinoma. | 9 |
| 31353022 | 2019 | Mutations in PIGU Impair the Function of the GPI Transamidase Complex, Causing Severe Intellectual Disability, Epilepsy, and Brain Anomalies. | 21 |
| 30171988 | 2019 | PIGU overexpression adds value to TNM staging in the prognostic stratification of patients with hepatocellular carcinoma. | 9 |
| 31353022 | 2019 | Mutations in PIGU Impair the Function of the GPI Transamidase Complex, Causing Severe Intellectual Disability, Epilepsy, and Brain Anomalies. | 21 |
| 29764287 | 2018 | Function of a membrane-embedded domain evolutionarily multiplied in the GPI lipid anchor pathway proteins PIG-B, PIG-M, PIG-U, PIG-W, PIG-V, and PIG-Z. | 9 |
| 29764287 | 2018 | Function of a membrane-embedded domain evolutionarily multiplied in the GPI lipid anchor pathway proteins PIG-B, PIG-M, PIG-U, PIG-W, PIG-V, and PIG-Z. | 9 |
| 30053080 | 2017 | Post-translational Regulation of Radioactive Iodine Therapy Response in Papillary Thyroid Carcinoma. | 14 |
| 30053080 | 2017 | Post-translational Regulation of Radioactive Iodine Therapy Response in Papillary Thyroid Carcinoma. | 14 |
| 21048031 | 2011 | Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. | 5 |
Citation
Dessen P
PIGU (phosphatidylinositol glycan anchor biosynthesis class U)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45608/pigu-(phosphatidylinositol-glycan-anchor-biosynthesis-class-u)
