Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 220296
MIM: 611642
HGNC: 26361
Ensembl: ENSG00000165478
Variants:
dbSNP: 220296
ClinVar: 220296
TCGA: ENSG00000165478
COSMIC: HEPACAM
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165478 | ENST00000298251 | Q14CZ8 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34592353 | 2022 | Panobinostat reverses HepaCAM gene expression and suppresses proliferation by increasing histone acetylation in prostate cancer. | 5 |
| 34592353 | 2022 | Panobinostat reverses HepaCAM gene expression and suppresses proliferation by increasing histone acetylation in prostate cancer. | 5 |
| 33024272 | 2021 | Long noncoding RNA HOTAIR regulates the invasion and metastasis of prostate cancer by targeting hepaCAM. | 16 |
| 33024272 | 2021 | Long noncoding RNA HOTAIR regulates the invasion and metastasis of prostate cancer by targeting hepaCAM. | 16 |
| 31960914 | 2020 | Structural basis for the dominant or recessive character of GLIALCAM mutations found in leukodystrophies. | 8 |
| 32335882 | 2020 | [Analysis of a child with megalencephalic leukoencephalopathy with subcortical cyst type 2B caused by HEPACAM variant]. | 0 |
| 31960914 | 2020 | Structural basis for the dominant or recessive character of GLIALCAM mutations found in leukodystrophies. | 8 |
| 32335882 | 2020 | [Analysis of a child with megalencephalic leukoencephalopathy with subcortical cyst type 2B caused by HEPACAM variant]. | 0 |
| 30664187 | 2019 | HepaCAM inhibits cell proliferation and invasion in prostate cancer by suppressing nuclear translocation of the androgen receptor via its cytoplasmic domain. | 3 |
| 31372844 | 2019 | Identification in Chinese patients with GLIALCAM mutations of megalencephalic leukoencephalopathy with subcortical cysts and brain pathological study on Glialcam knock-in mouse models. | 5 |
| 30664187 | 2019 | HepaCAM inhibits cell proliferation and invasion in prostate cancer by suppressing nuclear translocation of the androgen receptor via its cytoplasmic domain. | 3 |
| 31372844 | 2019 | Identification in Chinese patients with GLIALCAM mutations of megalencephalic leukoencephalopathy with subcortical cysts and brain pathological study on Glialcam knock-in mouse models. | 5 |
| 29658567 | 2018 | HepaCAM inhibits the malignant behavior of castration-resistant prostate cancer cells by downregulating Notch signaling and PF-3084014 (a γ-secretase inhibitor) partly reverses the resistance of refractory prostate cancer to docetaxel and enzalutamide in vitro. | 18 |
| 29658567 | 2018 | HepaCAM inhibits the malignant behavior of castration-resistant prostate cancer cells by downregulating Notch signaling and PF-3084014 (a γ-secretase inhibitor) partly reverses the resistance of refractory prostate cancer to docetaxel and enzalutamide in vitro. | 18 |
| 28093267 | 2017 | Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b. | 24 |
Citation
Dessen P
HEPACAM (hepatic and glial cell adhesion molecule)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45612/hepacam-(hepatic-and-glial-cell-adhesion-molecule)
