Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 931
MIM: 112210
HGNC: 7315
Ensembl: ENSG00000156738
Variants:
dbSNP: 931
ClinVar: 931
TCGA: ENSG00000156738
COSMIC: MS4A1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hematopoietic cell lineage | KEGG | ko04640 |
| Hematopoietic cell lineage | KEGG | hsa04640 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164748364 | tositumomab | Chemical | LabelAnnotation | associated | |||
| PA164781375 | ibritumomab | Chemical | LabelAnnotation | associated | |||
| PA165291493 | ofatumumab | Chemical | LabelAnnotation | associated | |||
| PA166122586 | afutuzumab | Chemical | LabelAnnotation, MultilinkAnnotation | associated | 24795454 | ||
| PA451261 | rituximab | Chemical | LabelAnnotation | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37433400 | 2023 | Novel cell subtypes of SPP1 + S100P+, MS4A1-SPP1 + S100P+ were key subpopulations in intrahepatic cholangiocarcinoma. | 1 |
| 37433400 | 2023 | Novel cell subtypes of SPP1 + S100P+, MS4A1-SPP1 + S100P+ were key subpopulations in intrahepatic cholangiocarcinoma. | 1 |
| 35091527 | 2022 | MS4A1 as a Potential Independent Prognostic Factor of Breast Cancer Related to Lipid Metabolism and Immune Microenvironment Based on TCGA Database Analysis. | 6 |
| 35091527 | 2022 | MS4A1 as a Potential Independent Prognostic Factor of Breast Cancer Related to Lipid Metabolism and Immune Microenvironment Based on TCGA Database Analysis. | 6 |
| 33352466 | 2021 | MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment. | 17 |
| 34542773 | 2021 | Differential effects of CD20+ B cells and PD-L1+ immune cells on pathologic complete response and outcome: comparison between inflammatory breast cancer and locally advanced breast cancer patients. | 4 |
| 34654826 | 2021 | CD20 positive CD8 T cells are a unique and transcriptionally-distinct subset of T cells with distinct transmigration properties. | 12 |
| 34743199 | 2021 | CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles. | 2 |
| 33352466 | 2021 | MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment. | 17 |
| 34542773 | 2021 | Differential effects of CD20+ B cells and PD-L1+ immune cells on pathologic complete response and outcome: comparison between inflammatory breast cancer and locally advanced breast cancer patients. | 4 |
| 34654826 | 2021 | CD20 positive CD8 T cells are a unique and transcriptionally-distinct subset of T cells with distinct transmigration properties. | 12 |
| 34743199 | 2021 | CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles. | 2 |
| 31682318 | 2020 | CD20-positive primary nasal peripheral T-cell lymphoma: An analysis of one case and review of the literature. | 1 |
| 32056202 | 2020 | STIM1 knock-down decreases the affinity of obinutuzumab for CD20 by altering CD20 localization to Triton-soluble membrane. | 1 |
| 32079680 | 2020 | Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab. | 71 |
Citation
Dessen P
MS4A1 (membrane spanning 4-domains A1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45648/ms4a1-(membrane-spanning-4-domains-a1)
