IGFBPL1 (insulin like growth factor binding protein like 1)

2007-02-01  

Identity

HGNC
IGFBPL1
LOCATION
9p13.1
LOCUSID
347252
ALIAS
IGFBP-RP4,IGFBPRP4,bA113O24.1

Other Information

Locus ID:

NCBI: 347252
MIM: 610413
HGNC: 20081
Ensembl: ENSG00000137142

Variants:

dbSNP: 347252
ClinVar: 347252
TCGA: ENSG00000137142
COSMIC: IGFBPL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137142ENST00000377694Q8WX77

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
375270362023IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy.4
381572522023IGFBPL1 inhibits macrophage lipid accumulation by enhancing the activation of IGR1R/LXRα/ABCG1 pathway.0
375270362023IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy.4
381572522023IGFBPL1 inhibits macrophage lipid accumulation by enhancing the activation of IGR1R/LXRα/ABCG1 pathway.0
364820702022Neural precursor cells tune striatal connectivity through the release of IGFBPL1.5
364820702022Neural precursor cells tune striatal connectivity through the release of IGFBPL1.5
320416732020Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.15
320416732020Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.15
293915972018IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades.24
293915972018IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades.24
176345302007Epigenetic inactivation implies independent functions for insulin-like growth factor binding protein (IGFBP)-related protein 1 and the related IGFBPL1 in inhibiting breast cancer phenotypes.19
178848392007Involvement of insulin-like growth factor-binding protein-related protein 1 in decidualization of human endometrial stromal cells.7
176345302007Epigenetic inactivation implies independent functions for insulin-like growth factor binding protein (IGFBP)-related protein 1 and the related IGFBPL1 in inhibiting breast cancer phenotypes.19
178848392007Involvement of insulin-like growth factor-binding protein-related protein 1 in decidualization of human endometrial stromal cells.7
158453872005Identification of a novel insulin-like growth factor binding protein gene homologue with tumor suppressor like properties.10

Citation

Dessen P

IGFBPL1 (insulin like growth factor binding protein like 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45687/igfbpl1-(insulin-like-growth-factor-binding-protein-like-1)