IL31RA (interleukin 31 receptor A)

2007-02-01  

Identity

HGNC
IL31RA
LOCATION
5q11.2
LOCUSID
133396
ALIAS
CRL,CRL3,GLM-R,GLMR,GPL,IL-31RA,PLCA2,PRO21384,hGLM-R,zcytoR17
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 133396
MIM: 609510
HGNC: 18969
Ensembl: ENSG00000164509

Variants:

dbSNP: 133396
ClinVar: 133396
TCGA: ENSG00000164509
COSMIC: IL31RA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164509ENST00000297015Q8NI17
ENSG00000164509ENST00000354961Q8NI17
ENSG00000164509ENST00000359040Q8NI17
ENSG00000164509ENST00000396834A0A499FJ31
ENSG00000164509ENST00000396836Q8NI17
ENSG00000164509ENST00000490985Q8NI17
ENSG00000164509ENST00000611895A0A0C4DGU4
ENSG00000164509ENST00000651239A0A494BZY2
ENSG00000164509ENST00000652039A0A494C190
ENSG00000164509ENST00000652347Q8NI17

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
366510892023IL-31 and IL-31 receptor alpha in pemphigus: Contributors to more than just itch?2
380818682023Interleukin 31 receptor α promotes smooth muscle cell contraction and airway hyperresponsiveness in asthma.0
366510892023IL-31 and IL-31 receptor alpha in pemphigus: Contributors to more than just itch?2
380818682023Interleukin 31 receptor α promotes smooth muscle cell contraction and airway hyperresponsiveness in asthma.0
346423382021Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis.19
346423382021Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis.19
324599582020Feline Interleukin-31 Shares Overlapping Epitopes with the Oncostatin M Receptor and IL-31RA.2
324599582020Feline Interleukin-31 Shares Overlapping Epitopes with the Oncostatin M Receptor and IL-31RA.2
284083972017The IL-31/IL-31 receptor axis: general features and role in tumor microenvironment.33
284083972017The IL-31/IL-31 receptor axis: general features and role in tumor microenvironment.33
252838442015The interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular lymphoma.17
252838442015The interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular lymphoma.17
243733532014A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1.233
246670972014Distribution of IL-31 and its receptor expressing cells in skin of atopic dermatitis.28
243733532014A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1.233

Citation

Dessen P

IL31RA (interleukin 31 receptor A)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45692/haematological-explorer/welcome