Identity
HGNC
LOCATION
12p12.3
LOCUSID
ALIAS
GLEPP1,NPHS6,PTP-OC,PTP-U2,PTPROT,PTPU2,R-PTP-O
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5800
MIM: 600579
HGNC: 9678
Ensembl: ENSG00000151490
Variants:
dbSNP: 5800
ClinVar: 5800
TCGA: ENSG00000151490
COSMIC: PTPRO
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38182570 | 2024 | Protein tyrosine phosphatase PTPRO represses lung adenocarcinoma progression by inducing mitochondria-dependent apoptosis and restraining tumor metastasis. | 0 |
| 38182570 | 2024 | Protein tyrosine phosphatase PTPRO represses lung adenocarcinoma progression by inducing mitochondria-dependent apoptosis and restraining tumor metastasis. | 0 |
| 35527665 | 2022 | PTPRO activates TLR4/NF-κB signaling to intensify lipopolysaccharide-induced pneumonia cell injury. | 3 |
| 36003382 | 2022 | PTPRO-related CD8(+) T-cell signatures predict prognosis and immunotherapy response in patients with breast cancer. | 7 |
| 35527665 | 2022 | PTPRO activates TLR4/NF-κB signaling to intensify lipopolysaccharide-induced pneumonia cell injury. | 3 |
| 36003382 | 2022 | PTPRO-related CD8(+) T-cell signatures predict prognosis and immunotherapy response in patients with breast cancer. | 7 |
| 34007244 | 2021 | MiR-6869-5p Induces M2 Polarization by Regulating PTPRO in Gestational Diabetes Mellitus. | 7 |
| 34719307 | 2021 | Protein tyrosine phosphatase receptor type O (PTPRO) knockdown enhances the proliferative, invasive and angiogenic activities of trophoblast cells by suppressing ER resident protein 44 (ERp44) expression in preeclampsia. | 1 |
| 34007244 | 2021 | MiR-6869-5p Induces M2 Polarization by Regulating PTPRO in Gestational Diabetes Mellitus. | 7 |
| 34719307 | 2021 | Protein tyrosine phosphatase receptor type O (PTPRO) knockdown enhances the proliferative, invasive and angiogenic activities of trophoblast cells by suppressing ER resident protein 44 (ERp44) expression in preeclampsia. | 1 |
| 31452237 | 2020 | PTPRO exaggerates inflammation in ulcerative colitis through TLR4/NF-κB pathway. | 9 |
| 32581055 | 2020 | IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma. | 74 |
| 31452237 | 2020 | PTPRO exaggerates inflammation in ulcerative colitis through TLR4/NF-κB pathway. | 9 |
| 32581055 | 2020 | IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma. | 74 |
| 30443949 | 2019 | MiRNA-548c-5p downregulates inflammatory response in preeclampsia via targeting PTPRO. | 26 |
Citation
Dessen P
PTPRO (protein tyrosine phosphatase receptor type O)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45721/ptpro-(protein-tyrosine-phosphatase-receptor-type-o)
