Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7181
MIM: 601529
HGNC: 7971
Ensembl: ENSG00000120798
Variants:
dbSNP: 7181
ClinVar: 7181
TCGA: ENSG00000120798
COSMIC: NR2C1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Generic Transcription Pathway | REACTOME | R-HSA-212436 |
| Nuclear Receptor transcription pathway | REACTOME | R-HSA-383280 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36591938 | 2023 | NamiRNA-enhancer network of miR-492 activates the NR2C1-TGF-β/Smad3 pathway to promote epithelial-mesenchymal transition of pancreatic cancer. | 5 |
| 36591938 | 2023 | NamiRNA-enhancer network of miR-492 activates the NR2C1-TGF-β/Smad3 pathway to promote epithelial-mesenchymal transition of pancreatic cancer. | 5 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 17010934 | 2006 | Transcriptional regulation of the human TR2 orphan receptor gene by nuclear factor 1-A. | 2 |
| 17010934 | 2006 | Transcriptional regulation of the human TR2 orphan receptor gene by nuclear factor 1-A. | 2 |
| 12615366 | 2003 | Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes. | 2 |
| 12949936 | 2003 | TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3. | 7 |
| 12615366 | 2003 | Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes. | 2 |
| 12949936 | 2003 | TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3. | 7 |
| 12093744 | 2002 | An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer. | 67 |
| 12093804 | 2002 | Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor. | 16 |
| 12093744 | 2002 | An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer. | 67 |
| 12093804 | 2002 | Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor. | 16 |
Citation
Dessen P
NR2C1 (nuclear receptor subfamily 2 group C member 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45733/nr2c1-(nuclear-receptor-subfamily-2-group-c-member-1)
