Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4734
MIM: 602278
HGNC: 7727
Ensembl: ENSG00000069869
Variants:
dbSNP: 4734
ClinVar: 4734
TCGA: ENSG00000069869
COSMIC: NEDD4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA451906 | warfarin | Chemical | ClinicalAnnotation | associated | PD | 27488176 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37962894 | 2024 | Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2. | 1 |
| 38108119 | 2024 | Deoxyribonuclease 1-like 3 inhibits colorectal malignancy through antagonizing NEDD4-triggered CDKN1A ubiquitination. | 0 |
| 38145746 | 2024 | Ubiquitin ligase NEDD4 promotes the proliferation of hepatocellular carcinoma cells through targeting PCDH17 protein for ubiquitination and degradation. | 1 |
| 38200519 | 2024 | PHB2 promotes SHIP2 ubiquitination via the E3 ligase NEDD4 to regulate AKT signaling in gastric cancer. | 2 |
| 38569496 | 2024 | Thrombospondin-1 Regulates Trophoblast Necroptosis via NEDD4-Mediated Ubiquitination of TAK1 in Preeclampsia. | 1 |
| 38634270 | 2024 | DMT1 ubiquitination by Nedd4 protects against ferroptosis after intracerebral hemorrhage. | 1 |
| 38783226 | 2024 | ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis. | 0 |
| 38888282 | 2024 | The Role of Ubiquitination and the E3 Ligase Nedd4 in Regulating Corneal Epithelial Wound Healing. | 0 |
| 37962894 | 2024 | Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2. | 1 |
| 38108119 | 2024 | Deoxyribonuclease 1-like 3 inhibits colorectal malignancy through antagonizing NEDD4-triggered CDKN1A ubiquitination. | 0 |
| 38145746 | 2024 | Ubiquitin ligase NEDD4 promotes the proliferation of hepatocellular carcinoma cells through targeting PCDH17 protein for ubiquitination and degradation. | 1 |
| 38200519 | 2024 | PHB2 promotes SHIP2 ubiquitination via the E3 ligase NEDD4 to regulate AKT signaling in gastric cancer. | 2 |
| 38569496 | 2024 | Thrombospondin-1 Regulates Trophoblast Necroptosis via NEDD4-Mediated Ubiquitination of TAK1 in Preeclampsia. | 1 |
| 38634270 | 2024 | DMT1 ubiquitination by Nedd4 protects against ferroptosis after intracerebral hemorrhage. | 1 |
| 38783226 | 2024 | ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis. | 0 |
Citation
Dessen P
NEDD4 (NEDD4 E3 ubiquitin protein ligase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45752/nedd4-(nedd4-e3-ubiquitin-protein-ligase)
