Identity
HGNC
LOCATION
10q26.11
LOCUSID
ALIAS
AOP-1,AOP1,HBC189,MER5,PRO1748,SP-22,prx-III
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10935
MIM: 604769
HGNC: 9354
Ensembl: ENSG00000165672
Variants:
dbSNP: 10935
ClinVar: 10935
TCGA: ENSG00000165672
COSMIC: PRDX3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165672 | ENST00000298510 | P30048 |
| ENSG00000165672 | ENST00000298510 | A0A384MTR2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Detoxification of Reactive Oxygen Species | REACTOME | R-HSA-3299685 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38097136 | 2024 | USP7-mediated ERβ stabilization mitigates ROS accumulation and promotes osimertinib resistance by suppressing PRDX3 SUMOylation in non-small cell lung carcinoma. | 0 |
| 38097136 | 2024 | USP7-mediated ERβ stabilization mitigates ROS accumulation and promotes osimertinib resistance by suppressing PRDX3 SUMOylation in non-small cell lung carcinoma. | 0 |
| 37312219 | 2023 | Knockdown of circSOD2 ameliorates osteoarthritis progression via the miR-224-5p/PRDX3 axis. | 2 |
| 37312219 | 2023 | Knockdown of circSOD2 ameliorates osteoarthritis progression via the miR-224-5p/PRDX3 axis. | 2 |
| 32125187 | 2022 | LncRNA LUADT1 inhibits cell apoptosis in diabetic retinopathy by regulating miR-383/peroxiredoxin 3 axis. | 6 |
| 34369396 | 2022 | Confirmation of PRDX3 c.568G>C as the Genetic Basis of Punctiform and Polychromatic Pre-Descemet Corneal Dystrophy. | 2 |
| 35303681 | 2022 | A quantitative proteomic analysis reveals the potential roles of PRDX3 in neurite outgrowth in N2a-APPswe cells. | 1 |
| 35723197 | 2022 | Silencing of B7-H4 induces intracellular oxidative stress and inhibits cell viability of breast cancer cells via downregulating PRDX3. | 2 |
| 36647961 | 2022 | PRDX3 promotes resistance to cisplatin in gastric cancer cells. | 0 |
| 32125187 | 2022 | LncRNA LUADT1 inhibits cell apoptosis in diabetic retinopathy by regulating miR-383/peroxiredoxin 3 axis. | 6 |
| 34369396 | 2022 | Confirmation of PRDX3 c.568G>C as the Genetic Basis of Punctiform and Polychromatic Pre-Descemet Corneal Dystrophy. | 2 |
| 35303681 | 2022 | A quantitative proteomic analysis reveals the potential roles of PRDX3 in neurite outgrowth in N2a-APPswe cells. | 1 |
| 35723197 | 2022 | Silencing of B7-H4 induces intracellular oxidative stress and inhibits cell viability of breast cancer cells via downregulating PRDX3. | 2 |
| 36647961 | 2022 | PRDX3 promotes resistance to cisplatin in gastric cancer cells. | 0 |
| 33889951 | 2021 | Biallelic loss-of-function variations in PRDX3 cause cerebellar ataxia. | 13 |
Citation
Dessen P
PRDX3 (peroxiredoxin 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45771/prdx3-(peroxiredoxin-3)
