Identity
HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
CONDBA,NOR-90,UBF,UBF-1,UBF1,UBF2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7343
MIM: 600673
HGNC: 12511
Ensembl: ENSG00000108312
Variants:
dbSNP: 7343
ClinVar: 7343
TCGA: ENSG00000108312
COSMIC: UBTF
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36448876 | 2023 | UBTF-internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia. | 7 |
| 37085611 | 2023 | UBTF tandem duplications define a distinct subtype of adult de novo acute myeloid leukemia. | 6 |
| 37236968 | 2023 | UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome. | 4 |
| 37603967 | 2023 | FGF13A interacts with NPM1 and UBF and inhibits the invasion of bladder cancer cells. | 0 |
| 36448876 | 2023 | UBTF-internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia. | 7 |
| 37085611 | 2023 | UBTF tandem duplications define a distinct subtype of adult de novo acute myeloid leukemia. | 6 |
| 37236968 | 2023 | UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome. | 4 |
| 37603967 | 2023 | FGF13A interacts with NPM1 and UBF and inhibits the invasion of bladder cancer cells. | 0 |
| 35192684 | 2022 | Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia. | 14 |
| 35316324 | 2022 | Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL. | 9 |
| 35192684 | 2022 | Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia. | 14 |
| 35316324 | 2022 | Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL. | 9 |
| 32350115 | 2020 | Protein kinase Cι promotes UBF1-ECT2 binding on ribosomal DNA to drive rRNA synthesis and transformed growth of non-small-cell lung cancer cells. | 6 |
| 32350115 | 2020 | Protein kinase Cι promotes UBF1-ECT2 binding on ribosomal DNA to drive rRNA synthesis and transformed growth of non-small-cell lung cancer cells. | 6 |
| 31217076 | 2019 | Ectopically expressed pNO40 suppresses ribosomal RNA synthesis by inhibiting UBF-dependent transcription activation. | 6 |
Citation
Dessen P
UBTF (upstream binding transcription factor)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45793/ubtf-(upstream-binding-transcription-factor)
