TXNDC17 (thioredoxin domain containing 17)

2007-02-01  

Identity

HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
TRP14,TXNL5
FUSION GENES

Other Information

Locus ID:

NCBI: 84817
MIM: 616967
HGNC: 28218
Ensembl: ENSG00000129235

Variants:

dbSNP: 84817
ClinVar: 84817
TCGA: ENSG00000129235
COSMIC: TXNDC17

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129235ENST00000250101Q9BRA2
ENSG00000129235ENST00000250101A0A140VJY7
ENSG00000129235ENST00000570330I3L2R6
ENSG00000129235ENST00000574734I3L0K2
ENSG00000129235ENST00000574838I3L3M7

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
388118532024TRP14 is the rate-limiting enzyme for intracellular cystine reduction and regulates proteome cysteinylation.0
388118532024TRP14 is the rate-limiting enzyme for intracellular cystine reduction and regulates proteome cysteinylation.0
333590852021Cellular S-denitrosylases: Potential role and interplay of Thioredoxin, TRP14, and Glutaredoxin systems in thiol-dependent protein denitrosylation.4
333590852021Cellular S-denitrosylases: Potential role and interplay of Thioredoxin, TRP14, and Glutaredoxin systems in thiol-dependent protein denitrosylation.4
256074662015TXNDC17 promotes paclitaxel resistance via inducing autophagy in ovarian cancer.85
256074662015TXNDC17 promotes paclitaxel resistance via inducing autophagy in ovarian cancer.85
247782502014Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase.74
247782502014Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase.74
185795192008Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha.49
185795192008Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha.49
146078432004Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways.29
146078442004Identification and characterization of TRP14, a thioredoxin-related protein of 14 kDa. New insights into the specificity of thioredoxin function.35
153559592004Structural basis of cellular redox regulation by human TRP14.12
146078432004Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways.29
146078442004Identification and characterization of TRP14, a thioredoxin-related protein of 14 kDa. New insights into the specificity of thioredoxin function.35

Citation

Dessen P

TXNDC17 (thioredoxin domain containing 17)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45804/txndc17-(thioredoxin-domain-containing-17)