Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8877
MIM: 603730
HGNC: 11240
Ensembl: ENSG00000176170
Variants:
dbSNP: 8877
ClinVar: 8877
TCGA: ENSG00000176170
COSMIC: SPHK1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38135696 | 2024 | SPHK1 potentiates colorectal cancer progression and metastasis via regulating autophagy mediated by TRAF6-induced ULK1 ubiquitination. | 1 |
| 38200582 | 2024 | Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis. | 0 |
| 38953574 | 2024 | Interference with sphingosine kinase-1 reduces the hydrogen peroxide-induced oxidative stress damage in melanocytes through four and a half LIM domains 2. | 0 |
| 38135696 | 2024 | SPHK1 potentiates colorectal cancer progression and metastasis via regulating autophagy mediated by TRAF6-induced ULK1 ubiquitination. | 1 |
| 38200582 | 2024 | Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis. | 0 |
| 38953574 | 2024 | Interference with sphingosine kinase-1 reduces the hydrogen peroxide-induced oxidative stress damage in melanocytes through four and a half LIM domains 2. | 0 |
| 36348017 | 2023 | DNA methylation status of the SPHK1 and LTB genes underlies the clinicopathological diversity of non-alcoholic steatohepatitis-related hepatocellular carcinomas. | 0 |
| 36823149 | 2023 | HOXC11 drives lung adenocarcinoma progression through transcriptional regulation of SPHK1. | 1 |
| 37467634 | 2023 | Sphingosine kinase 1 regulates lipid metabolism to promote progression of kidney renal clear cell carcinoma. | 0 |
| 37543362 | 2023 | Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production. | 0 |
| 37944444 | 2023 | The role of SphK/S1P/S1PR signaling pathway in bone metabolism. | 0 |
| 36348017 | 2023 | DNA methylation status of the SPHK1 and LTB genes underlies the clinicopathological diversity of non-alcoholic steatohepatitis-related hepatocellular carcinomas. | 0 |
| 36823149 | 2023 | HOXC11 drives lung adenocarcinoma progression through transcriptional regulation of SPHK1. | 1 |
| 37467634 | 2023 | Sphingosine kinase 1 regulates lipid metabolism to promote progression of kidney renal clear cell carcinoma. | 0 |
| 37543362 | 2023 | Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production. | 0 |
Citation
Dessen P
SPHK1 (sphingosine kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45829/sphk1-(sphingosine-kinase-1)
