Identity
HGNC
LOCATION
3p22.3
LOCUSID
ALIAS
CC-CKR-4,CD194,CKR4,CMKBR4,ChemR13,HGCN:14099,K5-5
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1233
MIM: 604836
HGNC: 1605
Ensembl: ENSG00000183813
Variants:
dbSNP: 1233
ClinVar: 1233
TCGA: ENSG00000183813
COSMIC: CCR4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183813 | ENST00000330953 | P51679 |
| ENSG00000183813 | ENST00000330953 | A0N0Q1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37017529 | 2023 | Contributions of Ccr4 and Gcn2 to the Translational Response of C. neoformans to Host-Relevant Stressors and Integrated Stress Response Induction. | 1 |
| 37081509 | 2023 | Blockade of CCR4 breaks immune tolerance in chronic hepatitis B patients by modulating regulatory pathways. | 0 |
| 37846490 | 2023 | CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection. | 3 |
| 37017529 | 2023 | Contributions of Ccr4 and Gcn2 to the Translational Response of C. neoformans to Host-Relevant Stressors and Integrated Stress Response Induction. | 1 |
| 37081509 | 2023 | Blockade of CCR4 breaks immune tolerance in chronic hepatitis B patients by modulating regulatory pathways. | 0 |
| 37846490 | 2023 | CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection. | 3 |
| 35177591 | 2022 | Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell carcinoma. | 10 |
| 35222362 | 2022 | FOXP3/HAT1 Axis Controls Treg Infiltration in the Tumor Microenvironment by Inducing CCR4 Expression in Breast Cancer. | 21 |
| 35177591 | 2022 | Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell carcinoma. | 10 |
| 35222362 | 2022 | FOXP3/HAT1 Axis Controls Treg Infiltration in the Tumor Microenvironment by Inducing CCR4 Expression in Breast Cancer. | 21 |
| 32914944 | 2021 | Immune signature of CCR7(+) central memory T cells associates with disease severity and Immunoglobulin E in bronchial asthma. | 4 |
| 33668648 | 2021 | Identification of Phosphorylated Amino Acids in Human TNRC6A C-Terminal Region and Their Effects on the Interaction with the CCR4-NOT Complex. | 1 |
| 33784417 | 2021 | Upregulation of CCR4 in activated CD8(+) T cells indicates enhanced lung homing in patients with severe acute SARS-CoV-2 infection. | 20 |
| 34887419 | 2021 | RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation. | 13 |
| 32914944 | 2021 | Immune signature of CCR7(+) central memory T cells associates with disease severity and Immunoglobulin E in bronchial asthma. | 4 |
Citation
Dessen P
CCR4 (C-C motif chemokine receptor 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45869/ccr4-(c-c-motif-chemokine-receptor-4)
