Identity
HGNC
LOCATION
14q22.1
LOCUSID
ALIAS
ERO1-L,ERO1-L-alpha,ERO1-alpha,ERO1L,ERO1LA,Ero1alpha
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 30001
MIM: 615435
HGNC: 13280
Ensembl: ENSG00000197930
Variants:
dbSNP: 30001
ClinVar: 30001
TCGA: ENSG00000197930
COSMIC: ERO1A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38402623 | 2024 | SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA. | 2 |
| 38454454 | 2024 | Biological mechanisms and clinical significance of endoplasmic reticulum oxidoreductase 1 alpha (ERO1α) in human cancer. | 1 |
| 38402623 | 2024 | SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA. | 2 |
| 38454454 | 2024 | Biological mechanisms and clinical significance of endoplasmic reticulum oxidoreductase 1 alpha (ERO1α) in human cancer. | 1 |
| 37659621 | 2023 | ERO1α primes the ryanodine receptor to respond to arsenite with concentration dependent Ca(2+) release sequentially triggering two different mechanisms of ROS formation. | 0 |
| 37769655 | 2023 | Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity. | 6 |
| 37776473 | 2023 | ERO1α promotes the proliferation and inhibits apoptosis of colorectal cancer cells by regulating the PI3K/AKT pathway. | 0 |
| 37659621 | 2023 | ERO1α primes the ryanodine receptor to respond to arsenite with concentration dependent Ca(2+) release sequentially triggering two different mechanisms of ROS formation. | 0 |
| 37769655 | 2023 | Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity. | 6 |
| 37776473 | 2023 | ERO1α promotes the proliferation and inhibits apoptosis of colorectal cancer cells by regulating the PI3K/AKT pathway. | 0 |
| 35189109 | 2022 | Crosstalk between ERO1α and ryanodine receptor in arsenite-dependent mitochondrial ROS formation. | 6 |
| 35785492 | 2022 | ERO1L promotes the proliferation and metastasis of lung adenocarcinoma via the Wnt2/β-catenin signaling pathway. | 3 |
| 35853086 | 2022 | Endoplasmic reticulum oxidoreductin 1-alpha deficiency and activation of protein translation synergistically impair breast tumour resilience. | 6 |
| 36063727 | 2022 | ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA. | 6 |
| 35189109 | 2022 | Crosstalk between ERO1α and ryanodine receptor in arsenite-dependent mitochondrial ROS formation. | 6 |
Citation
Dessen P
ERO1A (endoplasmic reticulum oxidoreductase 1 alpha)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45895/ero1a-(endoplasmic-reticulum-oxidoreductase-1-alpha)
