CD160 (CD160 molecule)

2007-02-01 Affiliation

Identity

HGNC

CD160

LOCATION

1q21.1

LOCUSID

11126

ALIAS

BY55,NK1,NK28

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 11126
MIM: 604463
HGNC: 17013
Ensembl: ENSG00000117281

Variants:

dbSNP: 11126
ClinVar: 11126
TCGA: ENSG00000117281
COSMIC: CD160

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000117281	ENST00000235933	O95971
ENSG00000117281	ENST00000235933	Q6FH89
ENSG00000117281	ENST00000369288	O95971
ENSG00000117281	ENST00000369288	Q6FH89
ENSG00000117281	ENST00000401557	O95971
ENSG00000117281	ENST00000584442	O95971
ENSG00000117281	ENST00000616463	O95971

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Immune System	REACTOME	R-HSA-168256
Adaptive Immune System	REACTOME	R-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	REACTOME	R-HSA-198933

References

Pubmed ID	Year	Title	Citations
18193050	2008	CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator.	113
22916009	2012	CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction.	70
20237496	2010	New genetic associations detected in a host response study to hepatitis B vaccine.	27
15494480	2004	Cutting edge: engagement of CD160 by its HLA-C physiological ligand triggers a unique cytokine profile secretion in the cytotoxic peripheral blood NK cell subset.	25
23761635	2013	CD160 activation by herpesvirus entry mediator augments inflammatory cytokine production and cytolytic function by NK cells.	23
11978774	2002	BY55/CD160 acts as a co-receptor in TCR signal transduction of a human circulating cytotoxic effector T lymphocyte subset lacking CD28 expression.	18
19109136	2009	Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation.	17
17237375	2007	A soluble form of the MHC class I-specific CD160 receptor is released from human activated NK lymphocytes and inhibits cell-mediated cytotoxicity.	15
26269596	2015	Biased Gs versus Gq proteins and β-arrestin signaling in the NK1 receptor determined by interactions in the water hydrogen bond network.	13
20164468	2010	CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia.	12

Citation

Dessen P

CD160 (CD160 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45911/cd160-(cd160-molecule)