FABP2 (fatty acid binding protein 2)

2007-02-01  

Identity

HGNC
LOCATION
4q26
LOCUSID
ALIAS
FABPI,I-FABP
FUSION GENES

Other Information

Locus ID:

NCBI: 2169
MIM: 134640
HGNC: 3556
Ensembl: ENSG00000145384

Variants:

dbSNP: 2169
ClinVar: 2169
TCGA: ENSG00000145384
COSMIC: FABP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145384ENST00000274024P12104

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
PPAR signaling pathwayKEGGko03320
PPAR signaling pathwayKEGGhsa03320
Fat digestion and absorptionKEGGko04975
Fat digestion and absorptionKEGGhsa04975
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysisREACTOMER-HSA-163560

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
182821092008Adaptations to climate in candidate genes for common metabolic disorders.116
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
145634462003Intestinal-type and liver-type fatty acid-binding protein in the intestine. Tissue distribution and clinical utility.84
179751192008Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.65
206738682010A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).36
198785692009Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.28
155986902005Polymorphisms in the fatty acid-binding protein 2 and apolipoprotein C-III genes are associated with the metabolic syndrome and dyslipidemia in a South Indian population.26
155986902005Polymorphisms in the fatty acid-binding protein 2 and apolipoprotein C-III genes are associated with the metabolic syndrome and dyslipidemia in a South Indian population.26
186604892008Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.26
194992402009Localization, function and regulation of the two intestinal fatty acid-binding protein types.26

Citation

Dessen P

FABP2 (fatty acid binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45921/fabp2-(fatty-acid-binding-protein-2)