CPNE1 (copine 1)

2007-02-01  

Identity

HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
COPN1,CPN1
FUSION GENES

Other Information

Locus ID:

NCBI: 8904
MIM: 604205
HGNC: 2314
Ensembl: ENSG00000214078

Variants:

dbSNP: 8904
ClinVar: 8904
TCGA: ENSG00000214078
COSMIC: CPNE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000214078ENST00000317677B0QZ18
ENSG00000214078ENST00000352393Q99829
ENSG00000214078ENST00000397442A6PVH9
ENSG00000214078ENST00000397443Q99829
ENSG00000214078ENST00000401607E7ENH5
ENSG00000214078ENST00000412056Q5JX52
ENSG00000214078ENST00000414664Q5JX44
ENSG00000214078ENST00000414711Q5JX54
ENSG00000214078ENST00000415920H0Y524
ENSG00000214078ENST00000416778Q5JX61
ENSG00000214078ENST00000420363Q5JX59
ENSG00000214078ENST00000430570Q5JX45
ENSG00000214078ENST00000434795Q5JX58
ENSG00000214078ENST00000435747Q5JX53
ENSG00000214078ENST00000437100Q5JX55
ENSG00000214078ENST00000437340F2Z2V0
ENSG00000214078ENST00000439669E7EV27
ENSG00000214078ENST00000439806Q5JX60
ENSG00000214078ENST00000440240Q5JX56
ENSG00000214078ENST00000458038Q5JX57

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383551012024CPNE1, A Potential Therapeutic Target in Nasopharyngeal Carcinoma, Affects Cell Growth and Radiation Resistance.0
383551012024CPNE1, A Potential Therapeutic Target in Nasopharyngeal Carcinoma, Affects Cell Growth and Radiation Resistance.0
380628112023Silencing of CPNE1-TRAF2 Axis Restrains the Development of Pancreatic Cancer.2
380628112023Silencing of CPNE1-TRAF2 Axis Restrains the Development of Pancreatic Cancer.2
349697452022Prognostic Value of Copine 1 in Patients With Renal Cell Carcinoma.3
351010552022CPNE1 promotes non-small cell lung cancer progression by interacting with RACK1 via the MET signaling pathway.8
357902712022Up-regulation of CPNE1 Appears to Enhance Cancer Progression in HER2-positive and Luminal A Breast Cancer Cells.3
363105112022Overexpression of Copines-1 is associated with clinicopathological parameters and poor outcome in gastric cancer.1
349697452022Prognostic Value of Copine 1 in Patients With Renal Cell Carcinoma.3
351010552022CPNE1 promotes non-small cell lung cancer progression by interacting with RACK1 via the MET signaling pathway.8
357902712022Up-regulation of CPNE1 Appears to Enhance Cancer Progression in HER2-positive and Luminal A Breast Cancer Cells.3
363105112022Overexpression of Copines-1 is associated with clinicopathological parameters and poor outcome in gastric cancer.1
321815262020CPNE1 predicts poor prognosis and promotes tumorigenesis and radioresistance via the AKT singling pathway in triple-negative breast cancer.24
321815262020CPNE1 predicts poor prognosis and promotes tumorigenesis and radioresistance via the AKT singling pathway in triple-negative breast cancer.24
292071392018CPNE1 silencing inhibits the proliferation, invasion and migration of human osteosarcoma cells.16

Citation

Dessen P

CPNE1 (copine 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45925/cpne1-(copine-1)