Identity
HGNC
LOCATION
Xp22.11
LOCUSID
ALIAS
DC21,KFSD,KFSDX,SAT,SSAT,SSAT-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6303
MIM: 313020
HGNC: 10540
Ensembl: ENSG00000130066
Variants:
dbSNP: 6303
ClinVar: 6303
TCGA: ENSG00000130066
COSMIC: SAT1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36907504 | 2023 | MYC-driven U2SURP regulates alternative splicing of SAT1 to promote triple-negative breast cancer progression. | 2 |
| 36907504 | 2023 | MYC-driven U2SURP regulates alternative splicing of SAT1 to promote triple-negative breast cancer progression. | 2 |
| 35977808 | 2022 | Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus. | 5 |
| 35977808 | 2022 | Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus. | 5 |
| 34658100 | 2021 | ASMTL-AS1 impedes the malignant progression of lung adenocarcinoma by regulating SAT1 to promote ferroptosis. | 13 |
| 34658100 | 2021 | ASMTL-AS1 impedes the malignant progression of lung adenocarcinoma by regulating SAT1 to promote ferroptosis. | 13 |
| 31283007 | 2020 | Identification of TAF1, SAT1, and ARHGEF9 as DNA methylation biomarkers for hepatocellular carcinoma. | 13 |
| 32432721 | 2020 | Dengue virus targets RBM10 deregulating host cell splicing and innate immune response. | 33 |
| 31283007 | 2020 | Identification of TAF1, SAT1, and ARHGEF9 as DNA methylation biomarkers for hepatocellular carcinoma. | 13 |
| 32432721 | 2020 | Dengue virus targets RBM10 deregulating host cell splicing and innate immune response. | 33 |
| 31352009 | 2019 | Knockdown of SSATX, an alternative splicing variant of the SAT1 gene, promotes melanoma progression. | 7 |
| 31399646 | 2019 | Spermidine/spermine N1-acetyltransferase 1 is a gene-specific transcriptional regulator that drives brain tumor aggressiveness. | 19 |
| 31352009 | 2019 | Knockdown of SSATX, an alternative splicing variant of the SAT1 gene, promotes melanoma progression. | 7 |
| 31399646 | 2019 | Spermidine/spermine N1-acetyltransferase 1 is a gene-specific transcriptional regulator that drives brain tumor aggressiveness. | 19 |
| 27901475 | 2017 | Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells. | 31 |
Citation
Dessen P
SAT1 (spermidine/spermine N1-acetyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45929/sat1
