CIRBP (cold inducible RNA binding protein)

2007-02-01  

Identity

HGNC
CIRBP
LOCATION
19p13.3
LOCUSID
1153
ALIAS
CIRP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1153
MIM: 602649
HGNC: 1982
Ensembl: ENSG00000099622

Variants:

dbSNP: 1153
ClinVar: 1153
TCGA: ENSG00000099622
COSMIC: CIRBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099622ENST00000320936Q14011
ENSG00000099622ENST00000320936Q53XX5
ENSG00000099622ENST00000413636Q14011
ENSG00000099622ENST00000444172F6WMK9
ENSG00000099622ENST00000585630Q14011
ENSG00000099622ENST00000585630Q53XX5
ENSG00000099622ENST00000585913K7EPM4
ENSG00000099622ENST00000585914K7EQR7
ENSG00000099622ENST00000586472Q14011
ENSG00000099622ENST00000586472Q53XX5
ENSG00000099622ENST00000586548K7EMY9
ENSG00000099622ENST00000586636K7EPM4
ENSG00000099622ENST00000586773K7EPM4
ENSG00000099622ENST00000587169K7EQL0
ENSG00000099622ENST00000587323D6W5Y5
ENSG00000099622ENST00000587896D6W5Y5
ENSG00000099622ENST00000588030Q14011
ENSG00000099622ENST00000588030Q53XX5
ENSG00000099622ENST00000588090Q14011
ENSG00000099622ENST00000588090Q53XX5
ENSG00000099622ENST00000588230D6W5Y5
ENSG00000099622ENST00000588344K7ELV6
ENSG00000099622ENST00000588411K7EJV5
ENSG00000099622ENST00000589235K7EPM4
ENSG00000099622ENST00000589266K7ENX8
ENSG00000099622ENST00000589686K7EJV1
ENSG00000099622ENST00000589710D6W5Y5
ENSG00000099622ENST00000590171K7EIF7
ENSG00000099622ENST00000590347K7ELT6
ENSG00000099622ENST00000591055K7ELT6
ENSG00000099622ENST00000591097K7EIF7
ENSG00000099622ENST00000591376K7EQL0
ENSG00000099622ENST00000591659K7ER40
ENSG00000099622ENST00000591935K7EPM4
ENSG00000099622ENST00000592051K7EQX4
ENSG00000099622ENST00000592234K7ELL4
ENSG00000099622ENST00000592412K7EQL0
ENSG00000099622ENST00000592815K7ENN6
ENSG00000099622ENST00000593048K7EQL0
ENSG00000099622ENST00000628979D6W5Y5

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
240971892013Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis.83
150752392004Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism.79
192779902009Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity.30
191582772009Cold-inducible RNA-binding protein bypasses replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activation.28
251873862014Stress response protein cirp links inflammation and tumorigenesis in colitis-associated cancer.25
263613902015The Cold-Inducible RNA-Binding Protein (CIRP) Level in Peripheral Blood Predicts Sepsis Outcome.20
234373862013NF-κB-dependent role for cold-inducible RNA binding protein in regulating interleukin 1β.15
234373862013NF-κB-dependent role for cold-inducible RNA binding protein in regulating interleukin 1β.15
266737122016Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner.15
261885052015Cold-inducible RNA-binding protein, CIRP, inhibits DNA damage-induced apoptosis by regulating p53.14

Citation

Dessen P

CIRBP (cold inducible RNA binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45930/cirbp-(cold-inducible-rna-binding-protein)