Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2528
MIM: 136836
HGNC: 4017
Ensembl: ENSG00000156413
Variants:
dbSNP: 2528
ClinVar: 2528
TCGA: ENSG00000156413
COSMIC: FUT6
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Glycosphingolipid biosynthesis - lacto and neolacto series | KEGG | ko00601 |
| Glycosphingolipid biosynthesis - lacto and neolacto series | KEGG | hsa00601 |
| Metabolic pathways | KEGG | hsa01100 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36151332 | 2023 | FUT6 inhibits the proliferation, migration, invasion, and EGF-induced EMT of head and neck squamous cell carcinoma (HNSCC) by regulating EGFR/ERK/STAT signaling pathway. | 6 |
| 36151332 | 2023 | FUT6 inhibits the proliferation, migration, invasion, and EGF-induced EMT of head and neck squamous cell carcinoma (HNSCC) by regulating EGFR/ERK/STAT signaling pathway. | 6 |
| 34215830 | 2021 | FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression. | 5 |
| 34215830 | 2021 | FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression. | 5 |
| 32901486 | 2020 | Using Eukaryotic Expression Systems to Generate Human α1,3-Fucosyltransferases That Effectively Create Selectin-Binding Glycans on Stem Cells. | 3 |
| 32901486 | 2020 | Using Eukaryotic Expression Systems to Generate Human α1,3-Fucosyltransferases That Effectively Create Selectin-Binding Glycans on Stem Cells. | 3 |
| 30307499 | 2019 | Whole genome sequence association with E-selectin levels reveals loss-of-function variant in African Americans. | 10 |
| 30742932 | 2019 | HOTAIR/miR-326/FUT6 axis facilitates colorectal cancer progression through regulating fucosylation of CD44 via PI3K/AKT/mTOR pathway. | 37 |
| 30808544 | 2019 | Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines. | 7 |
| 30307499 | 2019 | Whole genome sequence association with E-selectin levels reveals loss-of-function variant in African Americans. | 10 |
| 30742932 | 2019 | HOTAIR/miR-326/FUT6 axis facilitates colorectal cancer progression through regulating fucosylation of CD44 via PI3K/AKT/mTOR pathway. | 37 |
| 30808544 | 2019 | Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines. | 7 |
| 28334792 | 2017 | GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians. | 17 |
| 28771224 | 2017 | miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway. | 61 |
| 28334792 | 2017 | GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians. | 17 |
Citation
Dessen P
FUT6 (fucosyltransferase 6)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45954/fut6
