Identity
HGNC
LOCATION
9q32
LOCUSID
ALIAS
AGP-A,AGP1,HEL-S-153w,ORM
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5004
MIM: 138600
HGNC: 8498
Ensembl: ENSG00000229314
Variants:
dbSNP: 5004
ClinVar: 5004
TCGA: ENSG00000229314
COSMIC: ORM1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000229314 | ENST00000259396 | P02763 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA451906 | warfarin | Chemical | VariantAnnotation | not associated | 19794411 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36696913 | 2023 | Multiallelic Copy Number Variation in ORM1 is Associated with Plasma Cell-Free DNA Levels as an Intermediate Phenotype for Venous Thromboembolism. | 0 |
| 37640741 | 2023 | Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization. | 3 |
| 36696913 | 2023 | Multiallelic Copy Number Variation in ORM1 is Associated with Plasma Cell-Free DNA Levels as an Intermediate Phenotype for Venous Thromboembolism. | 0 |
| 37640741 | 2023 | Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization. | 3 |
| 35188865 | 2022 | Characterization of alpha-1-acid glycoprotein as a potential biomarker for breast cancer. | 5 |
| 35272364 | 2022 | Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk. | 4 |
| 35765957 | 2022 | ORM 1 as a biomarker of increased vascular invasion and decreased sorafenib sensitivity in hepatocellular carcinoma. | 4 |
| 36462134 | 2022 | Evaluation of IFIT3 and ORM1 as Biomarkers for Discriminating Active Tuberculosis from Latent Infection. | 3 |
| 35188865 | 2022 | Characterization of alpha-1-acid glycoprotein as a potential biomarker for breast cancer. | 5 |
| 35272364 | 2022 | Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk. | 4 |
| 35765957 | 2022 | ORM 1 as a biomarker of increased vascular invasion and decreased sorafenib sensitivity in hepatocellular carcinoma. | 4 |
| 36462134 | 2022 | Evaluation of IFIT3 and ORM1 as Biomarkers for Discriminating Active Tuberculosis from Latent Infection. | 3 |
| 33070381 | 2021 | Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils. | 4 |
| 33459949 | 2021 | miR-362-3p Targets Orosomucoid 1 to Promote Cell Proliferation, Restrain Cell Apoptosis and Thereby Mitigate Hypoxia/Reoxygenation-Induced Cardiomyocytes Injury. | 3 |
| 33580265 | 2021 | Proteomic Profile of Urinary Extracellular Vesicles Identifies AGP1 as a Potential Biomarker of Primary Aldosteronism. | 9 |
Citation
Dessen P
ORM1 (orosomucoid 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45955/orm1-(orosomucoid-1)
