Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 153572
MIM: 606198
HGNC: 14359
Ensembl: ENSG00000170561
Variants:
dbSNP: 153572
ClinVar: 153572
TCGA: ENSG00000170561
COSMIC: IRX2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170561 | ENST00000302057 | Q9BZI1 |
| ENSG00000170561 | ENST00000382611 | Q9BZI1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32422864 | 2020 | Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease. | 3 |
| 32422864 | 2020 | Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease. | 3 |
| 26062523 | 2015 | IRX2-mediated upregulation of MMP-9 and VEGF in a PI3K/AKT-dependent manner. | 8 |
| 26560478 | 2015 | Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells. | 10 |
| 26062523 | 2015 | IRX2-mediated upregulation of MMP-9 and VEGF in a PI3K/AKT-dependent manner. | 8 |
| 26560478 | 2015 | Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells. | 10 |
| 24806332 | 2014 | Knockdown of IRX2 inhibits osteosarcoma cell proliferation and invasion by the AKT/MMP9 signaling pathway. | 10 |
| 24806332 | 2014 | Knockdown of IRX2 inhibits osteosarcoma cell proliferation and invasion by the AKT/MMP9 signaling pathway. | 10 |
| 22210879 | 2012 | Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study. | 57 |
| 22210879 | 2012 | Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study. | 57 |
| 18421076 | 2008 | A genome-wide scan maps a novel high myopia locus to 5p15. | 40 |
| 18421076 | 2008 | A genome-wide scan maps a novel high myopia locus to 5p15. | 40 |
| 16752383 | 2006 | Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas. | 15 |
| 16752383 | 2006 | Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas. | 15 |
Citation
Dessen P
IRX2 (iroquois homeobox 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45962
