UBE2Q2 (ubiquitin conjugating enzyme E2 Q2)

2007-02-01  

Identity

HGNC
UBE2Q2
LOCATION
15q24.2
LOCUSID
92912
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 92912
MIM: 612501
HGNC: 19248
Ensembl: ENSG00000140367

Variants:

dbSNP: 92912
ClinVar: 92912
TCGA: ENSG00000140367
COSMIC: UBE2Q2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140367ENST00000267938Q8WVN8
ENSG00000140367ENST00000426727E9PHD0
ENSG00000140367ENST00000561723H3BV95
ENSG00000140367ENST00000561851Q8WVN8
ENSG00000140367ENST00000567921H3BN94
ENSG00000140367ENST00000569423Q8WVN8

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Ubiquitin mediated proteolysisKEGGko04120
Ubiquitin mediated proteolysisKEGGhsa04120
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168
Protein ubiquitinationREACTOMER-HSA-8852135
Synthesis of active ubiquitin: roles of E1 and E2 enzymesREACTOMER-HSA-8866652

References

Pubmed IDYearTitleCitations
267450682015Promoter Methylation Status of Two Novel Human Genes, UBE2Q1 and UBE2Q2, in Colorectal Cancer: a New Finding in Iranian Patients.9
267450682015Promoter Methylation Status of Two Novel Human Genes, UBE2Q1 and UBE2Q2, in Colorectal Cancer: a New Finding in Iranian Patients.9
226422442012Expression of UBE2Q2, a putative member of the ubiquitin-conjugating enzyme family in pediatric acute lymphoblastic leukemia.12
226422442012Expression of UBE2Q2, a putative member of the ubiquitin-conjugating enzyme family in pediatric acute lymphoblastic leukemia.12
201938422010Overexpression of the novel human gene, UBE2Q2, in breast cancer.9
203831462010New loci associated with kidney function and chronic kidney disease.433
201938422010Overexpression of the novel human gene, UBE2Q2, in breast cancer.9
203831462010New loci associated with kidney function and chronic kidney disease.433
197238762009Ubiquitin-conjugating enzyme UBE2Q2 suppresses cell proliferation and is down-regulated in recurrent head and neck cancer.7
197238762009Ubiquitin-conjugating enzyme UBE2Q2 suppresses cell proliferation and is down-regulated in recurrent head and neck cancer.7
174712412007Inactivation of the ubiquitin conjugating enzyme UBE2Q2 causes a prophase arrest and enhanced apoptosis in response to microtubule inhibiting agents.9
174712412007Inactivation of the ubiquitin conjugating enzyme UBE2Q2 causes a prophase arrest and enhanced apoptosis in response to microtubule inhibiting agents.9
163007362006Analysis of a novel human gene, LOC92912, over-expressed in hypopharyngeal tumours.5
163007362006Analysis of a novel human gene, LOC92912, over-expressed in hypopharyngeal tumours.5

Citation

Dessen P

UBE2Q2 (ubiquitin conjugating enzyme E2 Q2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45984/ube2q2-(ubiquitin-conjugating-enzyme-e2-q2)